Evidence map›Paper›PMID 33029692›Full record

ArticleSleep & breathing = Schlaf & Atmung2021

Evaluation of sleep quality and restless legs syndrome in adult patients with sickle cell anemia.

Nazan Şimşek Erdem, Ramazan Erdem, Gönül Oktay, Erdal Kurtoğlu

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Article in Sleep & breathing = Schlaf & Atmung, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Nazan Şimşek ErdemNeurology Department, Akdeniz University Hospital, B/BLOK 1. Floor. Dumlupınar Bulv. No: 55 07060, Konyaaltı, Antalya, Turkey. naazansimsek@hotmail.com.ORCID http://orcid.org/0000-0003-4612-1062
Ramazan ErdemHematology Department, Antalya Training and Research Hospital, Varlık, Kazım Karabekir Cd. 07100, Muratpaşa, Antalya, Turkey.
Gönül OktayHemoglobinopathy Clinic Center, Hatay/Antakya State Hospital, Güzelburç Mahallesi Kıbrıs Cd. No: 81, Antakya, Hatay, Turkey.
Erdal KurtoğluHematology Department, Antalya Training and Research Hospital, Varlık, Kazım Karabekir Cd. 07100, Muratpaşa, Antalya, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the prevalence of poor sleep quality and RLS in adult patients with sickle cell anemia (SCA). The second aim was to identify the risk factors for RLS and impairment of sleep quality in SCA patients. MATERIALS AND

methodsPatients at least 18 years old, with hemoglobin electrophoresis confirmation of sickle cell disease, were included. Restless legs syndrome was diagnosed according to the International Restless Legs Syndrome Study Group criteria. The sleep quality of the patients was determined using the Pittsburgh Sleep Quality Index (PSQI) scale. The Epworth Sleepiness Scale (ESS) was used to assess excessive daytime sleepiness.

resultsOf 72 patients enrolled in the study, the median total PSQI score was 5 (R 1-17). The total PSQI score was significantly associated with increased age and number of acute severe or extremely severe painful crises during the previous year (p < 0.001, r = 0.45; p = 0.013, r = 0.291 respectively). Of 72 patients, 13 (18%) had RLS and 11 (15%) had excessive daytime sleepiness. The presence of RLS was significantly associated with increased age (p = 0.004). The presence of RLS was not associated with fetal hemoglobin, hemoglobin, hematocrit, or ferritin levels (p > 0.05 for all).

conclusionThe prevalence of RLS among this sample of adult patients with sickle cell anemia was much higher than that previously reported for the general Turkish population. The presence of RLS was an important cause of sleep disturbance in these adult patients with SCA.

Indexed as

Sleep QualityAdultAnemia, Sickle CellDisorders of Excessive SomnolenceFemaleHumansMaleMiddle AgedPrevalenceRestless Legs SyndromeSleep Wake DisordersTurkeyYoung AdultAdult patientsPoor sleep qualityRestless legs syndromesickle cell anemia

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.