ReviewSkeletal radiology2021
Edema-like marrow signal intensity: a narrative review with a pictorial essay.
Review in Skeletal radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 46 citations in OpenAlex.
- Exploratory MRI and Clinical Marker Analysis of Pustulotic Arthro-Osteitis Disease Activity From a Phase 3 Brodalumab Trial.The Journal of dermatology · 2026Trial
- Bone marrow edema as an independent imaging predictor of dedifferentiated chondrosarcoma.Journal of orthopaedic surgery and research · 2026Article
- Bone-marrow edema estimation with a microwave imaging open-ended coaxial probe array in ex vivo bovine long bones: comparison with CT.European radiology experimental · 2026Article
- [Research advances on subchondral insufficiency fracture and osteonecrosis of the knee].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Review
- Beyond the Signal: Imaging Insights and Diagnostic Relevance of Bone Oedema in Bone Tumours and Tumour-like Lesions.Cancers · 2025Review
- The multifaceted roles of extracellular vesicles in osteonecrosis of the femoral head.Journal of orthopaedic translation · 2025Review
- Pictorial review: challenges in distinguishing bilateral metaphyseal marrow abnormalities on magnetic resonance imaging.Pediatric radiology · 2024Review
- Radiological Insights into Sacroiliitis: A Narrative Review.Clinics and practice · 2024Review
- Subchondral insufficiency fractures, subchondral insufficiency fractures with osteonecrosis, and other apparently spontaneous subchondral bone lesions of the knee-pathogenesis and diagnosis at imaging.Insights into imaging · 2023Review
- Edema-like marrow signal intensity (ELMSI) associated with nonossifying fibroma (NOF) on MRI: an uncommon finding in a common bone lesion.Skeletal radiology · 2023Article
- Prevalence of Asymptomatic Talar Bone Marrow Edema in Professional Ballet Dancers: Preliminary Data From a 2-Year Prospective Study.Orthopaedic journal of sports medicine · 2023Article
- Dual-energy CT virtual non-calcium: an accurate method for detection of knee osteoarthritis-related edema-like marrow signal intensity.Insights into imaging · 2023Article
- Spontaneous Bone Marrow Edema: Perfusion Abnormalities and Treatment with Surgical Decompression.International journal of molecular sciences · 2023Article
- Imaging of bone marrow pitfalls with emphasis on MRI.The British journal of radiology · 2023Review
- Sacroiliac Bone Marrow Edema: Innocent Until Proven Guilty?Arthritis & rheumatology (Hoboken, N.J.) · 2022Article
- MRI in axial spondyloarthritis: understanding an 'ASAS-positive MRI' and the ASAS classification criteria.Skeletal radiology · 2022Review
- Dual-Energy CT and Cinematic Rendering to Improve Assessment of Pelvic Fracture Instability.Radiology · 2022Article
- Automated segmentation of magnetic resonance bone marrow signal: a feasibility study.Pediatric radiology · 2022Article
- A Novel MRI Mapping Technique for Evaluating Bone Bruising Patterns Associated With Noncontact ACL Ruptures.Orthopaedic journal of sports medicine · 2022Article
- MRI in the Diagnosis and Treatment Response Assessment of Chronic Nonbacterial Osteomyelitis in Children and Adolescents.Current rheumatology reports · 2022Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The term edema-like marrow signal intensity (ELMSI) represents a general term describing an area of abnormal signal intensity at MRI. Its appearance includes absence of clear margins and the possibility of exceeding well-defined anatomical borders (for example, physeal scars). We can define "ELMSI with unknown cause" an entity where the characteristic MR appearance is associated with the absence of specific signs of an underlying condition. However, it is more often an important finding indicating the presence of an underlying disease, and we describe this case as "ELMSI with known cause." It presents a dynamic behavior and its evolution can largely vary. It initially corresponds to an acute inflammatory response with edema, before being variably replaced by more permanent marrow remodeling changes such as fibrosis or myxomatous connective tissue that can occur over time. It is important to study ELMSI variations over time in order to evaluate the activity state and therapeutic response of an inflammatory chronic joint disease, the resolution of a trauma, and the severity of an osteoarthritis. We propose a narrative review of the literature dealing with various subjects about this challenging topic that is imaging, temporal evolution, etiology, differential diagnoses, and possible organization, together with a pictorial essay.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.