Evidence map›Paper›PMID 33029541›Full record

ArticleJournal of immunology research2020

HMGB1 Recruits TET2/AID/TDG to Induce DNA Demethylation in STAT3 Promoter in CD4

Xuejun Xu, Yan Chen, Enyi Liu, Bin Fu, Juan Hua, Xu Chen, Yajing Xu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Targeting HMGB1: An available Therapeutic Strategy for Breast Cancer Therapy.International journal of biological sciences · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xuejun XuDepartment of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yan ChenDepartment of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Enyi LiuDepartment of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Bin FuDepartment of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Juan HuaDepartment of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Xu ChenDepartment of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yajing XuDepartment of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID https://orcid.org/0000-0001-9228-6648
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STAT3 is highly expressed in aGVHD CD4

Indexed as

DNA DemethylationPromoter Regions, GeneticAICDA (Activation-Induced Cytidine Deaminase)BiomarkersCD4-Positive T-LymphocytesCytidine DeaminaseDioxygenasesDisease SusceptibilityDNA-Binding ProteinsGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHMGB1 ProteinHumansProtein BindingProto-Oncogene ProteinsSTAT3 Transcription FactorAICDA (Activation-Induced Cytidine Deaminase)BiomarkersCytidine DeaminaseDioxygenasesDNA-Binding ProteinsHMGB1 ProteinProto-Oncogene ProteinsSTAT3 protein, humanSTAT3 Transcription FactorTET2 protein, human

Identifiers

PMID33029541
PMCPMC7532413
OpenAlexW3089005627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.