Evidence map›Paper›PMID 33029423›Full record

ArticleArab journal of urology2020

Multiparametric magnetic resonance imaging ultrasound-guided fusion biopsy during active surveillance: A single-centre study.

Kilian Röthlin, Stefania Zamboni, Marco Moschini, Patrick Stucki, Luca Afferi, Philipp Baumeister, Agostino Mattei

Open access · diamondAbstract read
In one paragraph

Article in Arab journal of urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kilian RöthlinDepartment of Urology, Luzerner Kantonsspital, Lucerne, Switzerland.
Stefania ZamboniDepartment of Urology, Luzerner Kantonsspital, Lucerne, Switzerland.
Marco MoschiniDepartment of Urology, Luzerner Kantonsspital, Lucerne, Switzerland.ORCID https://orcid.org/0000-0002-3084-2458
Patrick StuckiDepartment of Urology, Luzerner Kantonsspital, Lucerne, Switzerland.
Luca AfferiDepartment of Urology, Luzerner Kantonsspital, Lucerne, Switzerland.ORCID https://orcid.org/0000-0002-5472-1933
Philipp BaumeisterDepartment of Urology, Luzerner Kantonsspital, Lucerne, Switzerland.
Agostino MatteiDepartment of Urology, Luzerner Kantonsspital, Lucerne, Switzerland.
Luzerner Kantonsspital · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyse the role of multiparametric magnetic resonance imaging (mpMRI) ultrasound (US)-guided fusion biopsy (FB) in patients with low-risk prostate cancer (PCa) under active surveillance (AS). PATIENTS AND

methodsOur retrospective study included 47 patients under AS who consecutively underwent both FB and standard biopsy (SB), from May 2015 until November 2017. We defined FB as a transrectal US-guided biopsy based on mpMRI. The primary endpoint was to assess the rate of concordance between FB and SB in terms of diagnostic yield, as well as the rate of Gleason Score upgrading/downgrading between the two techniques. Cohen's kappa coefficient (κ) was applied to test the concordance between FB and SB.

resultsThe median (interquartile range [IQR]) follow-up was 20 (13-37) months. The median (IQR) number of cores taken was 13 (12-14) at SB and 4 (4-6) at FB. Overall, FB missed 12/47 (26%) PCa diagnoses compared to SB. There was concordance between SB and FB in 64% of the patients. The

conclusionIn our present study, FB showed no superiority over SB for the detection of PCa. On the contrary, FB had a high rate of missed PCa compared to SB. Further studies are required to ascertain the role of FB in AS. ABBREVIATIONS: AS: active surveillance; FB: fusion biopsy; IL: index lesion; IQR: interquartile range; mpMRI: multiparametric MRI; (cs)PCa: (clinically significant) prostate cancer; PI-RADS: Prostate Imaging-Reporting and Data System; PRIAS: Prostate Cancer Research International Active Surveillance; ROI: region of interest; SB: standard biopsy.

Indexed as

12-core template (standard) biopsyactive surveillancemultiparametric magnetic resonance imaging/ultrasound fusion biopsyProstate cancer

Identifiers

PMID33029423
PMCPMC7473102
OpenAlexW3016511452

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.