Evidence map›Paper›PMID 33029295›Full record

ArticleAnimal cells and systems2020

Inhibition of transient receptor potential melastatin 7 (TRPM7) protects against Schwann cell trans-dedifferentiation and proliferation during Wallerian degeneration.

Young Hwa Kim, Sumin Lee, Hyejin Yang, Yoo Lim Chun, Dokyoung Kim, Seung Geun Yeo, Chan Park, Junyang Jung, Youngbuhm Huh

Open access · goldAbstract read
In one paragraph

Article in Animal cells and systems, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Young Hwa KimDepartment of Anatomy and Neurobiology, College of Medicine, Kyung Hee University, Seoul, Korea.
Sumin LeeDepartment of Anatomy and Neurobiology, College of Medicine, Kyung Hee University, Seoul, Korea.
Hyejin YangDepartment of Anatomy and Neurobiology, College of Medicine, Kyung Hee University, Seoul, Korea.
Yoo Lim ChunDepartment of Anatomy and Neurobiology, College of Medicine, Kyung Hee University, Seoul, Korea.
Dokyoung KimDepartment of Anatomy and Neurobiology, College of Medicine, Kyung Hee University, Seoul, Korea.
Seung Geun YeoDepartment of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8021-1024
Chan ParkDepartment of Anatomy and Neurobiology, College of Medicine, Kyung Hee University, Seoul, Korea.
Junyang JungDepartment of Anatomy and Neurobiology, College of Medicine, Kyung Hee University, Seoul, Korea.ORCID https://orcid.org/0000-0003-3946-5406
Youngbuhm HuhDepartment of Anatomy and Neurobiology, College of Medicine, Kyung Hee University, Seoul, Korea.
Kyung Hee University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irreversible peripheral neurodegenerative diseases such as diabetic peripheral neuropathy are becoming increasingly common due to rising rates of diabetes mellitus; however, no effective therapeutic treatments have been developed. One of main causes of irreversible peripheral neurodegenerative diseases is dysfunction in Schwann cells, which are neuroglia unique to the peripheral nervous system (PNS). Because homeostasis of calcium (Ca

Indexed as

proliferationSchwann cellstrans-dedifferentiationTransient receptor potential melastatin 7 (TRPM7)Wallerian degeneration

Identifiers

PMID33029295
PMCPMC7473164
OpenAlexW3047569948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.