ArticleEvidence-based complementary and alternative medicine : eCAM2020
Curative Effect and Mechanism of Guiren Runchang Granules on Morphine-Induced Slow Transit Constipation in Mice.
Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- The influence of herbal medicine on serum motilin and its effect on human and animal model: a systematic review.Frontiers in pharmacology · 2023Pooled it
- Animal Models of Slow-Transit Constipation: Current Progress, Limitations, and Future Perspectives.Digestive diseases and sciences · 2026Review
- Opioid-Induced Constipation: Mechanistic Insights, Experimental Models, and Future Perspectives.Biomedicines · 2026Review
- Gastrodin alleviates loperamide-induced slow transit constipation in mice by modulating the MAPK signaling pathway.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Olive Oil Solution of Volatile Oil fromDrug design, development and therapy · 2025Article
- Guiren Runchang granules alleviate slow transit constipation in mice by modulating gut microbiota and short-chain fatty acids.Frontiers in microbiology · 2025Article
- The Potential Application of Aloe Barbadensis Mill. as Chinese Medicine for Constipation: Mini-Review.Drug design, development and therapy · 2024Review
- Therapeutic effects ofPharmaceutical biology · 2023Article
- The mechanism of intestinal flora dysregulation mediated by intestinal bacterial biofilm to induce constipation.Bioengineered · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent studies have identified the curative effects of traditional Chinese medicine for constipation. The mechanism of action of Guiren Runchang granules (GRGs) in the treatment of slow transit constipation (STC) was evaluated in this study. Here, we assessed the efficacy of GRG by comparing the differences in fecal characteristics, stool weight, and intestinal transit rate (ITR) among 6 groups (
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.