Evidence map›Paper›PMID 33029148›Full record

ArticleStem cells international2020

Essentiality of CTNNB1 in Malignant Transformation of Human Embryonic Stem Cells under Long-Term Suboptimal Conditions.

Jie Liu, Sicong Zeng, Yang Wang, Juan Yu, Qi Ouyang, Liang Hu, Di Zhou, Ge Lin, Yi Sun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cells international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jie LiuInstitute of Reproductive & Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha 410001, China.
Sicong ZengInstitute of Reproductive & Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha 410001, China.
Yang WangInstitute of Reproductive & Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha 410001, China.
Juan YuNational Engineering and Research Center of Human Stem Cells, Changsha 410001, China.
Qi OuyangInstitute of Reproductive & Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha 410001, China.
Liang HuInstitute of Reproductive & Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha 410001, China.
Di ZhouInstitute of Reproductive & Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha 410001, China.
Ge LinInstitute of Reproductive & Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha 410001, China.
Yi SunInstitute of Reproductive & Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha 410001, China.ORCID https://orcid.org/0000-0001-9238-976X
Central South University · CNNational Engineering Research Center of Human Stem Cells · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human embryonic stem cells (hESCs) gradually accumulate abnormal karyotypes during long-term suboptimal culture, which hinder their application in regenerative medicine. Previous studies demonstrated that the activation of

Identifiers

PMID33029148
PMCPMC7532415
OpenAlexW3088710759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.