Evidence map›Paper›PMID 33029056›Full record

ArticleJournal of clinical and experimental hepatology

Sarcopenia in Cirrhosis: Fallout on Liver Transplantation.

Vaibhaw Kumar, Jaya Benjamin, Varsha Shasthry, Kishore G Subramanya Bharathy, Piyush K Sinha, Guresh Kumar, Viniyendra Pamecha

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Pooled it
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  5. Review
  6. Article
  7. Cellular and molecular mechanisms of fatty infiltration in paraspinal muscles in spine-specific sarcopenia.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Review
  8. Post-surgical diets in the ERAS protocol: D-ERAS scoping review.European journal of clinical nutrition · 2026
    Article
  9. Article
  10. Article
  11. Bedside assessment of sarcopenia in hospitalized patients with liver cirrhosis: Magnitude and clinical implications.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Article
  12. Article
  13. Sarcopenia in cirrhosis: Unraveling the prevalence and relationships with liver disease severity and complications.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Vaibhaw KumarDepartment of Hepato Pancreato Biliary and Liver Transplant Surgery, Institute of Liver and Biliary Sciences, New Delhi, India.
Jaya BenjaminDepartment of Clinical Nutrition, Institute of Liver and Biliary Sciences, New Delhi, India.
Varsha ShasthryDepartment of Clinical Nutrition, Institute of Liver and Biliary Sciences, New Delhi, India.
Kishore G Subramanya BharathyDepartment of Hepato Pancreato Biliary and Liver Transplant Surgery, Institute of Liver and Biliary Sciences, New Delhi, India.
Piyush K SinhaDepartment of Hepato Pancreato Biliary and Liver Transplant Surgery, Institute of Liver and Biliary Sciences, New Delhi, India.
Guresh KumarDepartment of Clinical Research, Institute of Liver and Biliary Sciences, New Delhi, India.
Viniyendra PamechaDepartment of Hepato Pancreato Biliary and Liver Transplant Surgery, Institute of Liver and Biliary Sciences, New Delhi, India.
Institute of Liver and Biliary Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiver transplantation (LT) is a game changer in cirrhosis. Poor muscle mass defined as sarcopenia may potentially upset the LT scoreboard.

aimTo assess the prevalence and impact of sarcopenia on the intraoperative and early postoperative outcomes in Indian patients undergoing LT.

methodsPre LT, single-slice routine computed tomography images at L3 vertebra of 115 LT recipients were analyzed, to obtain cross-sectional area of six skeletal muscles normalized for height in m

resultsSarcopenia was found in 47.8% of patients [M (90.4%); age, 46.3 ± 10; BMI, 24.5 ± 4.3 kg/m2; child A:B:C = 1%:22%:77%; MELD, 20.6 ± 6.3; etiology alcohol: nonalchohol = 53%:47%; Charlson Comorbidity Index (CCI) > 3:≤3 = 56.5%:43.5%]. Sarcopenics vs. Nonsarcopenics; early postoperative complications: [sepsis, 49(89%) vs. 33(55%),

conclusionAlmost 50% of LT recipients had sarcopenia, who had a higher incidence of postoperative sepsis, neurological complications, longer ICU stay and ventilatory support. Low SMI, ACLF presentation, and intraoperative blood loss were the independent predictors of early mortality.

Indexed as

ACLF, Acute on chronic liver failureAKI, Acute kidney injuryasian indianBCM, Body cell massBT, Blood transfusionCCI, Charlson Comorbidity IndexCDC, Clavien-Dindo classificationchronic liver diseaseCNS, Central nervous systemCOPD, Chronic obstructive pulmonary diseaseCT, Computed tomographyECOG, Eastern Cooperative Oncology GroupEN, Enteral nutritionERAS, Enhanced recovery after surgeryESLD, End-stage liver diseaseEWGSOP, European Working Group on Sarcopenia in Older PeopleGRBWR, Graft recipient body weight ratioHAT, Hepatic artery thrombosisHE, Hepatic encephalopathyHU, Hounsfield UnitICU, Intensive care unitLDLT, Living donor liver transplantliver transplant outcomeLT, Liver transplantationMELD, Model for end-stage liver diseaseMHV, Middle hepatic veinNIV, Noninvasive ventilationnutritional statusORS, Oral rehydration solutionPMI, Psoas muscle indexPVT, Portal vein thrombosisSD, Standard deviationskeletal muscle areaSMA, Skeletal muscle areaSMI, Skeletal muscle index

Identifiers

PMID33029056
PMCPMC7527849
OpenAlexW2998474645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.