Evidence map›Paper›PMID 33028870›Full record

ArticleScientific reports2020

Synthesis and structure of a new thiazoline-based palladium(II) complex that promotes cytotoxicity and apoptosis of human promyelocytic leukemia HL-60 cells.

Javier Espino, Elena Fernández-Delgado, Samuel Estirado, Felipe de la Cruz-Martinez, Sergio Villa-Carballar, Emilio Viñuelas-Zahínos, Francisco Luna-Giles, José A Pariente

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

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  8. Antioxidant potential of nanomaterials.Turkish journal of biology = Turk biyoloji dergisi · 2023
    Review
  9. Article
  10. Novel Nickel(II), Palladium(II), and Platinum(II) Complexes withInternational journal of molecular sciences · 2022
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Javier EspinoDepartment of Physiology (Neuroimmunophysiology and Chrononutrition Research Group), Faculty of Science, University of Extremadura, 06006, Badajoz, Spain.
Elena Fernández-DelgadoDepartment of Physiology (Neuroimmunophysiology and Chrononutrition Research Group), Faculty of Science, University of Extremadura, 06006, Badajoz, Spain.
Samuel EstiradoDepartment of Physiology (Neuroimmunophysiology and Chrononutrition Research Group), Faculty of Science, University of Extremadura, 06006, Badajoz, Spain.
Felipe de la Cruz-MartinezDepartament of Organic and Inorganic Chemistry (Chemistry of Coordination Research Group), Faculty of Science, University of Extremadura, Badajoz, Spain.
Sergio Villa-CarballarDepartment of Physiology (Neuroimmunophysiology and Chrononutrition Research Group), Faculty of Science, University of Extremadura, 06006, Badajoz, Spain.
Emilio Viñuelas-ZahínosDepartament of Organic and Inorganic Chemistry (Chemistry of Coordination Research Group), Faculty of Science, University of Extremadura, Badajoz, Spain.
Francisco Luna-GilesDepartament of Organic and Inorganic Chemistry (Chemistry of Coordination Research Group), Faculty of Science, University of Extremadura, Badajoz, Spain.
José A ParienteDepartment of Physiology (Neuroimmunophysiology and Chrononutrition Research Group), Faculty of Science, University of Extremadura, 06006, Badajoz, Spain. pariente@unex.es.
Universidad de Extremadura · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cisplatin is one of the most widely used chemotherapeutic agents in the treatment of different tumors but has high toxicity and side effects. Therefore, the synthesis of new chemotherapeutic agents is necessary, so that they are effective in the treatment of cancer while avoiding such toxicity. In this study, we have synthesized and characterized a palladium(II) complex, [PdCl

Indexed as

Antineoplastic AgentsApoptosisCell DeathDNA DamageHL-60 CellsHumansAntineoplastic Agents

Identifiers

PMID33028870
PMCPMC7542172
OpenAlexW3092252834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.