Evidence map›Paper›PMID 33028761›Full record

ArticleJournal of clinical and experimental hematopathology : JCEH2020

An overlapping case of in situ mantle cell neoplasia and leukemic non-nodal mantle cell lymphoma.

Ryota Matsuoka, Noriaki Sakamoto, Mamiko Sakata-Yanagimoto, Shigeru Chiba, Masayuki Noguchi, Naoya Nakamura

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and experimental hematopathology : JCEH, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ryota MatsuokaDepartment of Diagnostic Pathology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Noriaki SakamotoDepartment of Diagnostic Pathology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Mamiko Sakata-YanagimotoDepartment of Hematology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Shigeru ChibaDepartment of Hematology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Masayuki NoguchiDepartment of Diagnostic Pathology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Naoya NakamuraDepartment of Pathology, Tokai University School of Medicine, Kanagawa, Japan.
University of Tsukuba · JPTokai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In situ mantle cell neoplasia (isMCN) and leukemic non-nodal mantle cell lymphoma (nnMCL) are classified as an indolent subtype of mantle cell lymphoma (MCL). The tumor cells of isMCN are restricted to the inner layer of the lymphoid tissue mantle zone, exhibiting an in situ pattern histologically. On the other hand, nnMCL is distributed in the peripheral blood, bone marrow and sometimes the spleen, but lymphadenopathy or systemic organ involvement is rare. We report a case of isMCN in a submandibular lymph node resected from a 65-year-old Japanese male. The tumor cells were positive for cyclin D1 (CCND1) and SOX11 expression, and were restricted to the mantle zone area of the lymph node. However, tumor cells were also detected in the stomach mucosa, bone marrow tissue and peripheral blood, suggesting nnMCL. isMCN and nnMCL may have a partly overlapping disease spectrum, although the correlation between these two subtypes has not been well described. This present case demonstrated characteristics overlapping between isMCN and nnMCL.

Indexed as

Head and Neck NeoplasmsLymph NodesLymphoma, Mantle-CellAgedCyclin D1HumansMaleSOXC Transcription FactorsCCND1 protein, humanCyclin D1SOX11 protein, humanSOXC Transcription Factorscyclin D1in situ mantle cell neoplasialeukemic non-nodal mantle cell lymphomaSOX11

Identifiers

PMID33028761
PMCPMC7810252
OpenAlexW3092336740

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.