Evidence map›Paper›PMID 33028744›Full record

SynthesisGut and liver2021

Technical and Clinical Aspects of Diagnostic Single-Balloon Enteroscopy in the First Decade of Use: A Systematic Review and Meta-Analysis.

Ye Gao, Lei Xin, Yi-Tong Zhang, Xiao-Rong Guo, Qian-Qian Meng, Zhao-Shen Li, Zhuan Liao

Open access · diamondAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Gut and liver, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Single balloon enteroscopy in the elderly.World journal of gastrointestinal endoscopy · 2025
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Observational
  9. Causes and Clinical Characteristics of Small Bowel Bleeding in Northern Vietnam.Canadian journal of gastroenterology & hepatology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ye GaoDepartment of Gastroenterology, Changhai Hospital, Naval Medical University, Shanghai, China.ORCID https://orcid.org/0000-0001-6273-880X
Lei XinDepartment of Gastroenterology, Changhai Hospital, Naval Medical University, Shanghai, China.ORCID https://orcid.org/0000-0002-8861-5055
Yi-Tong ZhangDepartment of Gastroenterology, Changhai Hospital, Naval Medical University, Shanghai, China.ORCID https://orcid.org/0000-0003-4092-8121
Xiao-Rong GuoDepartment of Gastroenterology, Changhai Hospital, Naval Medical University, Shanghai, China.ORCID https://orcid.org/0000-0002-7606-2174
Qian-Qian MengDepartment of Gastroenterology, Changhai Hospital, Naval Medical University, Shanghai, China.ORCID https://orcid.org/0000-0003-3218-3254
Zhao-Shen LiDepartment of Gastroenterology, Changhai Hospital, Naval Medical University, Shanghai, China.ORCID https://orcid.org/0000-0002-1650-4014
Zhuan LiaoDepartment of Gastroenterology, Changhai Hospital, Naval Medical University, Shanghai, China.ORCID https://orcid.org/0000-0002-2595-966X
Second Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsSingle-balloon enteroscopy (SBE) has been widely used in diagnosing small bowel disease. We conducted this study to systematically appraise its technical and clinical performance.

methodsStudies on SBE published by September 2018 were systematically searched. Technical and clinical performance data were collected and analyzed with descriptive or meta-analysis methods.

resultsIn total, 54 articles incorporating 4,592 patients (6,036 procedures) were included. Regarding technical parameters, the pooled insertion depths (IDs) for anterograde and retrograde SBE were 209.2 cm and 98.1 cm, respectively. The pooled retrograde ID in Asian countries was significantly greater than that in Western countries (129.0 cm vs 81.1 cm, p<0.001). The pooled anterograde and retrograde procedure times were 57.6 minutes and 65.1 minutes, respectively. The total enteroscopy rate was 21.9%, with no significant difference between Asian and Western countries. Clinically, the pooled diagnostic yield of SBE was 62.3%. Obscure gastrointestinal bleeding (OGIB) was the most common indication (50.0%), with a diagnostic yield of 59.5%. Vascular lesions were the most common findings in Western OGIB patients (76.9%) but not in Asian ones (31.0%). The rates of severe and mild adverse events were 0.5% and 2.5%, respectively.

conclusionsSBE is technically efficient and is clinically effective and safe, but total enteroscopy is relatively difficult to achieve with this technique. Etiologies of OGIB in Asian countries differ from those in Western countries.

Indexed as

Intestinal DiseasesSingle-Balloon EnteroscopyDouble-Balloon EnteroscopyEndoscopy, GastrointestinalGastrointestinal HemorrhageHumansIntestine, SmallDiagnosisMeta-analysisSingle-balloon enteroscopySystematic reviewTotal enteroscopy

Identifiers

PMID33028744
PMCPMC7960980
OpenAlexW3092446769

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.