Evidence map›Paper›PMID 33028697›Full record

ArticleBMJ global health2020

Long-term outcomes for children with disability and severe acute malnutrition in Malawi.

Natasha Lelijveld, Nora Groce, Seema Patel, Theresa Nnensa, Emmanuel Chimwezi, Melissa Gladstone, Macpherson Mallewa, Jonathan Wells, Andrew Seal, Marko Kerac

Open access · goldAbstract read
In one paragraph

Article in BMJ global health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Natasha LelijveldInstitute for Global Health, University College London, London, UK natasha.lelijveld.11@ucl.ac.uk.ORCID 0000-0002-8452-0198
Nora GroceDepartment of Epidemiology and Health Care, UCL International Disability Research Centre, London, UK.
Seema PatelDepartment of Epidemiology and Health Care, UCL International Disability Research Centre, London, UK.
Theresa NnensaClinical Research Programme, Malawi-Liverpool Wellcome Trust, Blantyre, Malawi.
Emmanuel ChimweziClinical Research Programme, Malawi-Liverpool Wellcome Trust, Blantyre, Malawi.
Melissa GladstoneInstitute of Translational Medicine, University of Liverpool, Liverpool, UK.ORCID 0000-0002-2579-9301
Macpherson MallewaDepartment of Paediatrics and Child Health, University of Malawi College of Medicine, Blantyre, Southern Region, Malawi.
Jonathan WellsChildhood Nutrition Research Centre, Institute of Child Health, University, London, UK.
Andrew SealInstitute for Global Health, University College London, London, UK.
Marko KeracClinical Research Programme, Malawi-Liverpool Wellcome Trust, Blantyre, Malawi.ORCID 0000-0002-3745-7317
University of Liverpool · GBUniversity College London · GBUniversity of Malawi · MW

Funding

Wellcome TrustWellcome Trust 101113/Z/13/A
6 · The paper itself

Abstract

introductionSevere acute malnutrition (SAM) and disability are major global health issues. Although they can cause and influence each other, data on their co-existence are sparse. We aimed to describe the prevalence and patterns of disability among a cohort of children with SAM.

methodsA longitudinal cohort study in Malawi followed SAM survivors up to 7 years postdischarge. Clinical and anthropometric profiles were compared with sibling and community controls. Disability at original admission was identified clinically; at 7-year follow-up a standardised screening tool called 'the Washington Group Questionnaire' was used.

results60/938 (6.4%) of admissions to SAM treatment had clinically obvious disability at admission. Post-treatment mortality was high, with only 11/60 (18%) surviving till 7-year follow-up. SAM children with a disability at admission had 6.99 (95% CI 3.49 to 14.02; p<0.001) greater risk of dying compared with children without disability. They were also older, less likely to be HIV positive or have oedema and more severely malnourished. Long-term survivors were more stunted, had less catch-up growth, smaller head circumference, weaker hand grip strength and poorer school achievement than non-disabled survivors.The Washington Group Questionnaire confirmed disability in all who had been identified clinically, and identified many who had not been previously flagged.

conclusionDisability is common among children affected by SAM. Those with disability-associated SAM have greatly increased risk of dying even if they survive the initial episode of malnutrition. Survivors have poorer growth, physical strength and school achievement. To enable all children to survive and thrive post-SAM, it is vital to focus more on those with disabilities. SAM treatment programmes should consider using not just clinical assessment but structured assessments to better identify at-risk individuals as well as understand the population of children for which they are developing services.

Indexed as

Children with DisabilitiesSevere Acute MalnutritionAftercareChildHand StrengthHumansLongitudinal StudiesMalawiPatient Dischargechild healthnutrition

Identifiers

PMID33028697
PMCPMC7542612
OpenAlexW3092192374

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.