Evidence map›Paper›PMID 33028645›Full record

ArticleCold Spring Harbor molecular case studies2020

Helicase-inactivating

Lara Kamal, Sarah B Pierce, Christina Canavati, Amal Abu Rayyan, Tamara Jaraysa, Orit Lobel, Suhair Lolas, Barbara M Norquist, Grace Rabie, Fouad Zahdeh and 3 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cold Spring Harbor molecular case studies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 4 countries.

Lara Kamal *Molecular Genetics Laboratory, Istishari Arab Hospital, Ramallah, Palestine.
Sarah B Pierce *Departments of Medicine and Genome Sciences, University of Washington, Seattle, Washington 98195, USA.
Christina CanavatiHereditary Research Laboratory and Department of Biology, Bethlehem University, Bethlehem, Palestine.
Amal Abu RayyanHereditary Research Laboratory and Department of Biology, Bethlehem University, Bethlehem, Palestine.
Tamara JaraysaHereditary Research Laboratory and Department of Biology, Bethlehem University, Bethlehem, Palestine.
Orit LobelMedical Genetics Institute, Shaare Zedek Medical Center, Jerusalem 9103102, Israel.
Suhair LolasHereditary Research Laboratory and Department of Biology, Bethlehem University, Bethlehem, Palestine.
Barbara M NorquistDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington 98195, USA.
Grace RabieHereditary Research Laboratory and Department of Biology, Bethlehem University, Bethlehem, Palestine.
Fouad ZahdehHereditary Research Laboratory and Department of Biology, Bethlehem University, Bethlehem, Palestine.
Ephrat Levy-LahadMedical Genetics Institute, Shaare Zedek Medical Center, Jerusalem 9103102, Israel.
Mary-Claire KingDepartments of Medicine and Genome Sciences, University of Washington, Seattle, Washington 98195, USA.
Moien N KanaanMolecular Genetics Laboratory, Istishari Arab Hospital, Ramallah, Palestine.
Bethlehem University · PSShaare Zedek Medical Center · ILUniversity of Washington · USRafik Hariri University Hospital · LBWoman's Cancer Foundation · US

Funding

GENOMIC ANALYSIS OF INHERITED BREAST AND OVARIAN CANCERR35CA197458 · NCI · UNIVERSITY OF WASHINGTON · PI KING, MARY-CLAIRE · 2015 to 2021
$6.4M
NCI NIH HHS R35 CA197458
6 · The paper itself

Abstract

Fanconi anemia is a genetically and phenotypically heterogeneous disorder characterized by congenital anomalies, bone marrow failure, cancer, and sensitivity of chromosomes to DNA cross-linking agents. One of the 22 genes responsible for Fanconi anemia is

Indexed as

AllelesAnus, ImperforateChild, PreschoolDNA-Binding ProteinsDNA HelicasesFamilyFanconi AnemiaFanconi Anemia Complementation Group ProteinsFemaleGenetic Predisposition to DiseaseHumansMaleMicrocephalyMutation, MissensePedigreePhenotypeBRIP1 protein, humanDNA-Binding ProteinsDNA HelicasesFanconi Anemia Complementation Group ProteinsRNA Helicasesanal atresiaaplasia/hypoplasia involving bones of the upper limbshand polydactylymicrocephalysmall for gestational age

Identifiers

PMID33028645
PMCPMC7552932
OpenAlexW3092376053

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.