Evidence map›Paper›PMID 33028614›Full record

ArticleDevelopment (Cambridge, England)2020

Kctd15 regulates nephron segment development by repressing Tfap2a activity.

Brooke E Chambers, Eleanor G Clark, Allison E Gatz, Rebecca A Wingert

Open access · greenAbstract read
In one paragraph

Article in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Frontiers in cell and developmental biology · 2024
    Article
  7. Article
  8. Review
  9. Principles of Zebrafish Nephron Segment Development.Journal of developmental biology · 2023
    Review
  10. Article
  11. Review
  12. Review
  13. Biomedicines · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Brooke E ChambersDepartment of Biological Sciences, Center for Stem Cells and Regenerative Medicine, Center for Zebrafish Research, University of Notre Dame, Notre Dame, IN 46556, USA rwingert@nd.edu bweaver4@nd.edu.
Eleanor G ClarkDepartment of Biological Sciences, Center for Stem Cells and Regenerative Medicine, Center for Zebrafish Research, University of Notre Dame, Notre Dame, IN 46556, USA.
Allison E GatzDepartment of Biological Sciences, Center for Stem Cells and Regenerative Medicine, Center for Zebrafish Research, University of Notre Dame, Notre Dame, IN 46556, USA.
Rebecca A WingertDepartment of Biological Sciences, Center for Stem Cells and Regenerative Medicine, Center for Zebrafish Research, University of Notre Dame, Notre Dame, IN 46556, USA rwingert@nd.edu bweaver4@nd.edu.ORCID 0000-0003-3133-7549
University of Notre Dame · US

Funding

Generation of novel models of kidney defects using the zebrafishR01DK100237 · NIDDK · UNIVERSITY OF NOTRE DAME · PI WINGERT, REBECCA ANN · 2013 to 2017
$1.8M
NIDDK NIH HHS R01 DK100237
6 · The paper itself

Abstract

A functional vertebrate kidney relies on structural units called nephrons, which are epithelial tubules with a sequence of segments each expressing a distinct repertoire of solute transporters. The transcriptiona`l codes driving regional specification, solute transporter program activation and terminal differentiation of segment populations remain poorly understood. Here, we demonstrate that the KCTD15 paralogs

Indexed as

AnimalsBody PatterningCell DifferentiationCell LineageEmbryonic DevelopmentEmbryo, NonmammalianEpitheliumGene Expression Regulation, DevelopmentalKidneyKidney TubulesNephronsOrganogenesisPotassium Channels, Voltage-GatedSignal TransductionSolute Carrier Family 12, Member 1Transcription Factor AP-2kctd15b protein, zebrafishPotassium Channels, Voltage-GatedSolute Carrier Family 12, Member 1tfap2a protein, zebrafishTranscription Factor AP-2Zebrafish ProteinsKctd15KidneyNephronSegmentationTfap2aZebrafish

Identifiers

PMID33028614
PMCPMC7758634
OpenAlexW3091853813

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.