Evidence map›Paper›PMID 33028534›Full record

ArticleScience advances2020

Fine structural tuning of the assembly of ECM peptide conjugates via slight sequence modifications.

Jingya Qin, Jennifer D Sloppy, Kristi L Kiick

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. The Chemistry and Biology of Collagen Hybridization.Journal of the American Chemical Society · 2023
    Review
  11. Article
  12. Article
  13. Click chemistry functionalization of self-assembling peptide hydrogels.Journal of biomedical materials research. Part A · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jingya QinDepartment of Materials Science and Engineering, University of Delaware, Newark, DE 19716, USA.ORCID 0000-0002-1680-0921
Jennifer D SloppyDepartment of Materials Science and Engineering, University of Delaware, Newark, DE 19716, USA.
Kristi L KiickDepartment of Materials Science and Engineering, University of Delaware, Newark, DE 19716, USA. kiick@udel.edu.ORCID 0000-0001-8587-0301
University of Delaware · USBiotechnology Institute · US

Funding

This renovation project will create over 1455 sq. ft. of state- of-the-art reseaP20GM104316 · NIGMS · UNIVERSITY OF DELAWARE · PI FOX, JOSEPH M · 2014 to 2024
$26.8M
Pilot Research Subproject ProgramP30GM110758 · NIGMS · UNIVERSITY OF DELAWARE · PI BEEBE, THOMAS PAUL · 2014 to 2018
$5.8M
COBRE on Membrane Protein Production and CharacterizationP30GM103519 · NIGMS · UNIVERSITY OF DELAWARE · PI LENHOFF, ABRAHAM M · 2012 to 2014
$3.3M
Collagen-based targeting for improving delivery and efficacy of osteoarthritis drugsR21AR069778 · NIAMS · UNIVERSITY OF DELAWARE · PI KIICK, KRISTI L, PRICE, CHRISTOPHER · 2017 to 2018
$365k
NIAMS NIH HHS R21 AR069778NIGMS NIH HHS P20 GM104316NIGMS NIH HHS P30 GM103519NIGMS NIH HHS P30 GM110758
6 · The paper itself

Abstract

The self-assembly of nanostructures from conjugates of elastin-like peptides and collagen-like peptides (ELP-CLP) has been studied as means to produce thermoresponsive, collagen-binding drug delivery vehicles. Motivated by our previous work in which ELP-CLP conjugates successfully self-assembled into vesicles and platelet-like nanostructures, here, we extend our library of ELP-CLP bioconjugates to a series of tryptophan/phenylalanine-containing ELPs and GPO-based CLPs [W

Identifiers

PMID33028534
PMCPMC7541060
OpenAlexW3092312656

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.