Evidence map›Paper›PMID 33028531›Full record

ArticleScience advances2020

Solution NMR readily reveals distinct structural folds and interactions in doubly

Owen B Becette, Guanghui Zong, Bin Chen, Kehinde M Taiwo, David A Case, T Kwaku Dayie

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 40 citations in OpenAlex.

  1. Journal of molecular biology · 2026
    Article
  2. Article
  3. Application of NMR to Large RNAs.Journal of molecular biology · 2025
    Review
  4. Article
  5. Review
  6. Selective [9-Chembiochem : a European journal of chemical biology · 2025
    Article
  7. Leveraging relaxation-optimizedNature chemistry · 2025
    Article
  8. Enhanced TROSY Effect in [2-Angewandte Chemie (International ed. in English) · 2024
    Article
  9. 2'-Frontiers in molecular biosciences · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. 4'-SCFAngewandte Chemie (International ed. in English) · 2022
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Synthesis of [7-Monatshefte fur chemie · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Owen B BecetteDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20782, USA.ORCID 0000-0002-3796-4933
Guanghui ZongDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20782, USA.ORCID 0000-0002-7335-039X
Bin ChenDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20782, USA.
Kehinde M TaiwoDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20782, USA.
David A CaseDepartment of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ 08854, USA.ORCID 0000-0003-2314-2346
T Kwaku DayieDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20782, USA. dayie@umd.edu.ORCID 0000-0002-7119-4362
University of Maryland, College Park · USRutgers, The State University of New Jersey · US

Funding

The Center for HIV RNA Studies (CRNA)U54AI150470 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHIU, WAH · 2019 to 2021
$15.1M
Inhibitor of FtsZ Polymerization in M. tuberculosisR01AI050470 · NIAID · SOUTHERN RESEARCH INSTITUTE · PI REYNOLDS, ROBERT C · 2002 to 2004
$1.7M
NIAID NIH HHS R01 AI050470NIAID NIH HHS U54 AI150470
6 · The paper itself

Abstract

RNAs form critical components of biological processes implicated in human diseases, making them attractive for small-molecule therapeutics. Expanding the sites accessible to nuclear magnetic resonance (NMR) spectroscopy will provide atomic-level insights into RNA interactions. Here, we present an efficient strategy to introduce

Indexed as

RNABase PairingHumansMagnetic Resonance SpectroscopyNuclear Magnetic Resonance, BiomolecularNucleic Acid ConformationRNA

Identifiers

PMID33028531
PMCPMC7541061
OpenAlexW3092162281

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.