ArticleCancer imaging : the official publication of the International Cancer Imaging Society2020
Extracellular volume fraction measurement correlates with lymphocyte abundance in thymic epithelial tumors.
Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed.
- Quantitative dual-energy computed tomography parameters as imaging biomarkers for assessing the histopathologic grade of colorectal cancer.Quantitative imaging in medicine and surgery · 2026Article
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- A multiparameter diagnostic model based on MRI volumetric ADC histogram and clinical variables accurately differentiates thymic epithelial tumors from mediastinal lymphomas.BMC medical imaging · 2026Article
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- Spectral computed tomography-based quantitative parameters combined with extracellular volume fraction to predict lymph node metastases in gastric cancer.European radiology · 2025Article
- Extracellular volume fraction quantification by equilibrium contrast-enhanced CT via automated segmentation predicts survival outcomes in bladder cancer: a propensity score-matched study.Annals of medicine · 2025Article
- Nomogram based on dual-energy computed tomography to predict the response to induction chemotherapy in patients with nasopharyngeal carcinoma: a two-center study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Article
- Re-examining What the Results of "a Measurement of Oxygen Level in Tissues" Really Mean.Molecular imaging and biology · 2024Article
- Dual-Energy Computed Tomography in Detecting and Predicting Lymph Node Metastasis in Malignant Tumor Patients: A Comprehensive Review.Diagnostics (Basel, Switzerland) · 2024Review
- Nomogram based on dual-energy CT-derived extracellular volume fraction for the prediction of microsatellite instability status in gastric cancer.Frontiers in oncology · 2024Article
- Correlations between contrast-enhanced CT-measured extracellular volume fraction, histopathological features, and MYCN amplification status in abdominal neuroblastoma: a retrospective study.Abdominal radiology (New York) · 2023Article
- Usefulness of Three-Dimensional Iodine Mapping Quantified by Dual-Energy CT for Differentiating Thymic Epithelial Tumors.Journal of clinical medicine · 2023Article
- T1 mapping and multimodel diffusion-weighted imaging in the assessment of cervical cancer: a preliminary study.The British journal of radiology · 2023Article
- Extracellular volume fraction determined by equilibrium contrast-enhanced CT for the prediction of the pathological complete response to neoadjuvant chemoradiotherapy for locally advanced rectal cancer.European radiology · 2023Article
- The use of quantitative T1-mapping to identify cells and collagen fibers in rectal cancer.Frontiers in oncology · 2023Article
- Diagnostic value of apparent diffusion coefficient in predicting pathological T stage in patients with thymic epithelial tumor.Cancer imaging : the official publication of the International Cancer Imaging Society · 2022Article
- Extracellular Volume Fraction Derived From Dual-Layer Spectral Detector Computed Tomography for Diagnosing Cervical Lymph Nodes Metastasis in Patients With Papillary Thyroid Cancer: A Preliminary Study.Frontiers in oncology · 2022Article
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7 authors.
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Abstract
backgroundRecent advance in tissue characterization with parametric mapping imaging has the potential to be a novel biomarker for histopathologic correlation with thymic epithelial tumors (TETs). The purpose of our study is to evaluate MRI T1 mapping with the calculation of extracellular volume (ECV) fraction for histologic correlation with thymic epithelial tumor based on lymphocyte abundance.
methodsA retrospective study including 31 consecutive patients (14 men and 17 women, median age, 56 years; interquartile range, 12 years) with TETs was performed. The T1 values and ECV were assessed by using quantitative MRI mapping techniques. Mann-Whitney U test, Kruskal-Wallis H test, and receiver operating characteristic curve analyses were used to assess discrimination between different types of TETs based on lymphocyte abundance.
resultsExtracellular volume was significantly higher in TETs with sparse lymphocyte, including type A, type B3, and thymic carcinoma, compared with those with abundant lymphocyte, including type B1, B2, and AB thymomas (42.5% vs 26.9%, respectively; p < 0.001). Extracellular volume was significantly higher in thymic carcinoma compared with low grade and high grade thymomas (48.6% vs 31.1% vs 27.6%, respectively; p = 0.002).
conclusionsT1 mapping with the calculation of extracellular volume (ECV) fraction correlate with the WHO histologic classification of thymic epithelial tumor based on lymphocyte abundance.
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