ArticleBMC complementary medicine and therapies2020
Isolation of endophytic bacteria from the leaves of Anredera cordifolia CIX1 for metabolites and their biological activities.
Article in BMC complementary medicine and therapies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- Unlocking the hidden potential of the genus Salvia through a systematic review of endophytic bacterial and fungal diversity and biotechnological prospects.Archives of microbiology · 2026Pooled it
- Isolation and characterization of endophytic bacteria from Echinacea purpurea and Calendula officinalis with antimicrobial and anticancer activities.BMC complementary medicine and therapies · 2026Article
- Formulation ofCurrent issues in molecular biology · 2026Article
- Exploration of bioflocculant production of endophytic bacterium: assessment of characteristics and efficiency of its bioflocculant in wastewater treatment.Environmental science and pollution research international · 2026Article
- Characterization and biological activities of endophytic bacteria from Vernonia anthelmintica flowers.Folia microbiologica · 2026Article
- A Review of Medicinal Plants from the Anak Dalam Tribe of Jambi: An Evaluation of Their Potential for Diabetic Wound Healing Effects-Current Status and Future Perspectives.Drug design, development and therapy · 2026Review
- A comprehensive review on bacterial endophytic secondary metabolites: a road map from crude extract to lead molecule production.Frontiers in pharmacology · 2026Review
- Endophytic Bacillus stercoris (VITSSSTJ4) an endophyte of Chaetomorpha antennina in the synthesis of lead molecule 1-(4-Acetamidoanilino)-3,7-dimethylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile against bacterial pathogens.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Regulatory Machinery of Bacterial Bioflocculant Synthesis and Optimisation and Assessment of Bioflocculation Efficiency in Wastewater.International journal of molecular sciences · 2025Article
- Quorum quenching by endophytic Bacillus cereus AL1: a lactonase-based anti-virulence strategy against Pseudomonas aeruginosa.BMC microbiology · 2025Article
- The Dual Role ofPlants (Basel, Switzerland) · 2025Article
- GC-MS profiling, in vitro and in silico antibacterial and antioxidant potential of crude secondary metabolites of an endophytic bacterium isolated from Enhydra fluctuans lour.Scientific reports · 2025Article
- Exploring the Antimicrobial, Antioxidant and Extracellular Enzymatic Activities of Culturable Endophytic Fungi Isolated from the Leaves ofMicroorganisms · 2025Article
- Bioactivity and metabolic profiling of crude extracts from endophytic bacteria linked toHeliyon · 2025Article
- Deciphering the nature and statistical optimization of antimicrobial metabolites of two endophytic bacilli.AMB Express · 2025Article
- Antibacterial Activity of Metabolites of EndophyticInternational journal of microbiology · 2025Article
- Antitumor and cytotoxic activities of endophytic Enterobacter hormaechei derived secondary metabolites: In-vitro and In-silico study.PloS one · 2025Article
- A Narrative Review of the Biological Activities ofJournal of experimental pharmacology · 2025Review
- Evaluation of antibacterial and anticancer properties of secondary metabolites isolated from soil Bacillus spp focusing on two strains of Bacillus licheniformis and Bacillus siamensis.BMC molecular and cell biology · 2024Article
- Isolation, identification, and biological characterization of bacterial endophytes isolated from Gunnera perpensa L.FEMS microbiology letters · 2024Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundEndophytes, especially those that are found from ethnopharmacologically noteworthy medicinal plants have attracted attention due to their diverse bioactive metabolites of pharmacological importance.
methodsThis study aimed at isolating endophytic bacterium from the leaves of Anredera cordifolia CIX1 for its bioactive metabolites. The endophytic isolates were identified by 16S rRNA sequence and investigated for antibiotic sensitivity using different antibiotics. The secondary metabolites were evaluated for antibacterial activity against four bacterial strains. The 2-diphenyl-1-picrylhydrazyl (DPPH) and 2, 2'-azinobis (3- ethylbenzothiazoline-6-sulfonic acid) (ABTS) methods were used to assess their scavenging activities. The chemical components were analysed by gas chromatography-mass spectrometry (GC-MS).
resultsOut of 13 isolates, Isolate 1 was identified as Pseudomonas aeruginosa CP043328.1. It was resistant to clindamycin, ertapenem, penicillin G, amoxicillin, cephalothin and kanamycin but sensitive to imipenem, meropenem, and gentamycin. Its extract demonstrated antibacterial activity with minimum inhibitory concentration value of 0.098 against Bacillus cereus (ATCC 10102) and Staphylococcus aureus (ATCC 25925) and 0.391 mg/ml against Escherichia coli (ATCC 25922) and Proteus mirabilis (ATCC 25933). The extract revealed DPPH and ABTS scavenging activities with half maximal inhibitory concentration value of 0.650 mg/ml and 0.15 mg/ml, respectively. The GC-MS revealed a total of 15 compounds with diisooctyl phthalate (50.51%) and [1, 2, 4] oxadiazole, 5-benzyl-3 (10.44%) as major components.
conclusionsP. aeruginosa CP043328.1 produced secondary metabolites with antibacterial and antioxidant activities.
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