Evidence map›Paper›PMID 33028229›Full record

ArticleBMC genomics2020

The algal selenoproteomes.

Liang Jiang, Yiqian Lu, Lin Zheng, Gaopeng Li, Lianchang Chen, Maona Zhang, Jiazuan Ni, Qiong Liu, Yan Zhang

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. An atlas of plant selenium metabolism.The New phytologist · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. The geneFrontiers in microbiology · 2024
    Article
  9. Scientific opinion on the tolerable upper intake level for selenium.EFSA journal. European Food Safety Authority · 2023
    Article
  10. Selenoprotein: Potential Player in Redox Regulation inAntioxidants (Basel, Switzerland) · 2022
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Liang JiangCollege of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong Province, 518060, P.R. China. jiangliang@szu.edu.cn.ORCID http://orcid.org/0000-0001-8598-5985
Yiqian LuCollege of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong Province, 518060, P.R. China.
Lin ZhengCollege of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong Province, 518060, P.R. China.
Gaopeng LiCollege of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong Province, 518060, P.R. China.
Lianchang ChenCollege of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong Province, 518060, P.R. China.
Maona ZhangCollege of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong Province, 518060, P.R. China.
Jiazuan NiCollege of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong Province, 518060, P.R. China.
Qiong LiuCollege of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong Province, 518060, P.R. China.
Yan ZhangCollege of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong Province, 518060, P.R. China. zhangyan@szu.edu.cn.
Shenzhen University · CN

Funding

National Natural Science Foundation of China 31401129
6 · The paper itself

Abstract

backgroundSelenium is an essential trace element, and selenocysteine (Sec, U) is its predominant form in vivo. Proteins that contain Sec are selenoproteins, whose special structural features include not only the TGA codon encoding Sec but also the SECIS element in mRNA and the conservation of the Sec-flanking region. These unique features have led to the development of a series of bioinformatics methods to predict and research selenoprotein genes. There have been some studies and reports on the evolution and distribution of selenoprotein genes in prokaryotes and multicellular eukaryotes, but the systematic analysis of single-cell eukaryotes, especially algae, has been very limited.

resultsIn this study, we predicted selenoprotein genes in 137 species of algae by using a program we previously developed. More than 1000 selenoprotein genes were obtained. A database website was built to record these algae selenoprotein genes ( www.selenoprotein.com ). These genes belong to 42 selenoprotein families, including three novel selenoprotein gene families.

conclusionsThis study reveals the primordial state of the eukaryotic selenoproteome. It is an important clue to explore the significance of selenium for primordial eukaryotes and to determine the complete evolutionary spectrum of selenoproteins in all life forms.

Indexed as

EukaryotaSeleniumSelenoproteinsCodon, TerminatorEvolution, MolecularProteomeSelenocysteineCodon, TerminatorProteomeSeleniumSelenocysteineSelenoproteinsAlgaeEvolutionGenomicsSeleniumSelenoprotein

Identifiers

PMID33028229
PMCPMC7539508
OpenAlexW3092355911

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.