ArticleBMC geriatrics2020
Effects of kidney function, serum albumin and hemoglobin on dementia severity in the oldest old people with newly diagnosed Alzheimer's disease in a residential aged care facility: a cross-sectional study.
Article in BMC geriatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- The role of serum albumin and albumin-related nutritional indices in predicting post-stroke cognitive impairment: a systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- Associations Between Kidney Function and Risk of Cognitive Impairment Among Chinese Older Adults.Geriatrics & gerontology international · 2026Article
- Article
- Serum 25-hydroxyvitamin D and cognitive performance in hospitalized older adults: a cross-sectional study from Central Poland.Frontiers in nutrition · 2026Article
- Association of Serum Albumin and the ApoB/ApoA1 Ratio with Acute Post-Stroke Cognitive Impairment: A Propensity Score-Matched Case-Control Study.International journal of general medicine · 2026Article
- Cognitive impairment in chronic kidney disease: mechanisms, clinical manifestations, and management strategies.Metabolic brain disease · 2025Review
- Analysis of influencing factors on the nutritional status of non-dialysis elderly patients with chronic kidney disease and depression.World journal of psychiatry · 2025Article
- Associations between neutrophil-lymphocyte ratio and risk of cognitive impairment among Chinese older adults.BMC geriatrics · 2025Article
- Explaining the Association Between Number of Teeth and Frailty in Older Chinese Adults: The Chain Mediating Effect of Nutritional Status and Cognitive Function.International journal of nursing practice · 2025Article
- Urinary bisphenol A and its substitutes exposure increased the risk of renal tubular injury (N-acetyl-Frontiers in public health · 2025Article
- Associations of prognostic nutritional index with cardiovascular all-cause mortality among CVD patients with diabetes or prediabetes: evidence from the NHANES 2005-2018.Frontiers in immunology · 2025Article
- Renal function and risk of dementia: a Mendelian randomization study.Renal failure · 2024Article
- Interactions between patterns of multimorbidity and functional status among hospitalized older patients: a novel approach using cluster analysis and association rule mining.Journal of translational medicine · 2024Article
- Importance of serum albumin in machine learning-based prediction of cognitive function in the elderly using a basic blood test.Frontiers in neurology · 2024Article
- An investigation into the potential association between nutrition and Alzheimer's disease.Frontiers in nutrition · 2024Article
- A glimpse into the future: revealing the key factors for survival in cognitively impaired patients.Frontiers in aging neuroscience · 2024Article
- Synergistic impact of plasma albumin and cognitive function on all-cause mortality in Chinese older adults: a prospective cohort study.Frontiers in nutrition · 2024Article
- Classification and deep-learning-based prediction of Alzheimer disease subtypes by using genomic data.Translational psychiatry · 2023Article
- Mild cognitive impairment in type 2 diabetes is associated with fibrinogen-to-albumin ratios.PeerJ · 2023Article
- A nomogram for predicting risk of death during hospitalization in elderly patients with Alzheimer's disease at the time of admission.Frontiers in neurology · 2023Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic kidney disease (CKD), low serum albumin, and anemia are known risk factors for cognitive decline in older people. We investigated the association between kidney function and cognitive impairment severity in oldest-old people with a diagnosis of Alzheimer's disease (AD).
methodsA cross-sectional study of patients aged 80 years and older was conducted at a veterans' home in Taiwan between 2012 and 2016. Their estimated glomerular filtration rate (eGFR) was determined using the Modification of Diet in Renal Diseases (MDRD) equation. Cognitive function was evaluated with the Mini-Mental State Examination (MMSE) and Clinical Dementia Rating (CDR).
resultsA total of 84 patients (age mean ± SD, 86.6 ± 3.9 years) had MMSE scores of 10.1 ± 6.7, and CDR scores of 1.6 ± 0.7. The average eGFR was 61.7 ± 21.5 mL/min/1.73m
conclusionsWe found dementia severity was significantly associated with kidney function, serum albumin, and hemoglobin in the oldest-old with AD. We recommend that oldest-old people with a diagnosis of AD be evaluated to determine kidney function, as well as nutritional and hematological status. Further study is needed to establish whether prevention of CKD deterioration, and correction of malnutrition and anemia may help to slow cognitive decline in oldest-old people with dementia.
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