Evidence map›Paper›PMID 33028028›Full record

ArticleMedicina (Kaunas, Lithuania)2020

Positive Anti-SSA/Ro Antibody in a Woman with SARS-CoV-2 Infection Using Immunophenotyping: A Case Report.

Po-I Huang, Ting-Chun Lin, Feng-Cheng Liu, Yi-Jung Ho, Jeng-Wei Lu, Te-Yu Lin

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Po-I HuangSchool of Medicine, National Defense Medical Center, Taipei 114, Taiwan.
Ting-Chun LinSchool of Pharmacy, National Defense Medical Center, Taipei 114, Taiwan.
Feng-Cheng LiuRheumatology/Immunology and Allergy, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.
Yi-Jung HoSchool of Pharmacy, National Defense Medical Center, Taipei 114, Taiwan.
Jeng-Wei LuDepartment of Biological Sciences, National University of Singapore, Singapore 117543, Singapore.ORCID 0000-0003-2128-2046
Te-Yu LinDivision of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.
Tri-Service General Hospital · TWNational Defense Medical Center · TWNational University of Singapore · SG

Funding

Ministry of Science and Technology, Taiwan MOST106-2314-B-016-026-MY3Tri-Service General Hospital TSGH-E-109238
6 · The paper itself

Abstract

The clinical spectrum of novel coronavirus infection appears to be wide, encompassing asymptomatic infection, mild upper respiratory tract illness, and severe viral pneumonia, with respiratory failure and even death. Autoantibodies, especially antiphospholipid antibodies, can occur in severe infections. Other autoantibodies are seldom reported. Here, a 60-year-old female patient without dry-mouth symptoms detected positive for anti-60 kDa SSA/Ro antibodies on day 43 after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. To investigate this unique clinical case of SARS-CoV-2 infection, immunological characteristics of this case were detected by using flow cytometry and were compared to the other three groups of patients-health subjects, 2019 novel coronavirus disease (COVID-19) recovery patients, and Sjögren's syndrome (SS) patients. Monitoring the autoantibody level and the development of subsequently related autoimmune diseases are warranted after SARS-CoV-2 infection.

Indexed as

ImmunophenotypingAntibodies, AntinuclearAntibodies, ViralBetacoronavirusCoronavirus InfectionsCOVID-19FemaleFlow CytometryHumansMiddle AgedPandemicsPneumonia, ViralSARS-CoV-2Sjogren's SyndromeAntibodies, AntinuclearAntibodies, ViralSS-A antibodiesautoimmuneCOVID-19immunophenotypingSARS-CoV-2Sjögren’s syndrome

Identifiers

PMID33028028
PMCPMC7600347
OpenAlexW3090140649

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.