Evidence map›Paper›PMID 33028018›Full record

ArticleViruses2020

Increased Monocyte Inflammatory Responses to Oxidized LDL Are Associated with Insulin Resistance in HIV-Infected Individuals on Suppressive Antiretroviral Therapy.

Brooks I Mitchell, Elizabeth I Laws, Dominic C Chow, Ivo N SahBandar, Louie Mar A Gangcuangco, Cecilia M Shikuma, Lishomwa C Ndhlovu

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Brooks I MitchellHawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96813, USA.
Elizabeth I LawsHawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96813, USA.
Dominic C ChowHawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96813, USA.
Ivo N SahBandarHawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96813, USA.
Louie Mar A GangcuangcoHawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96813, USA.ORCID 0000-0002-6714-9294
Cecilia M ShikumaHawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96813, USA.
Lishomwa C NdhlovuHawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96813, USA.
University of Hawaiʻi at Mānoa · US

Funding

The Role of gp120 on Cardiovascular Disease in People Living with HIVU54MD007601 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI Jane Chung-Do · 2017 to 2026
$59.5M
WORLDWIDE EPIDEMIOLOGY &EPIZOOTIOLOGY OF HANTAVIRUSG12RR003061 · NCRR · UNIVERSITY OF HAWAII AT MANOA · PI ALLEN, JOHN A · 1986 to 2011
$32.3M
RESEARCH DESIGN, BIOSTATISTICS AND RESEARCH ETHICS COREG12MD007601 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI BERRY, MARLA J · 2012 to 2016
$13.0M
Role of Oxidative Stress and Inflammation in HIV Cardiovascular RiskR01HL095135 · NHLBI · UNIVERSITY OF HAWAII AT MANOA · PI SHIKUMA, CECILIA M. · 2008 to 2012
$4.5M
NCRR NIH HHS G12 RR003061NHLBI NIH HHS R01 HL095135NIMHD NIH HHS G12 MD007601NIMHD NIH HHS U54 MD007601
6 · The paper itself

Abstract

Despite long term antiretroviral therapy (ART), insulin resistance (IR) is common among people living with HIV/AIDS (PLWHA) exposing this population to a greater risk of cardiometabolic complications when compared to their uninfected counterparts. We previously identified an expansion in monocyte subpopulations in blood that were linked to the degree of IR in persons with HIV on stable ART. In this study, we directly assessed monocyte inflammatory functional properties from PLWHA on ART (

Indexed as

Insulin ResistanceAntirheumatic AgentsBlood GlucoseCardiometabolic Risk FactorsCytokinesFastingFemaleHIV InfectionsHumansInterleukin-1betaInterleukin-6Interleukin-8Leukocytes, MononuclearLipoproteins, LDLMaleMiddle AgedAntirheumatic AgentsBlood GlucoseCytokinesIL1B protein, humanInterleukin-1betaInterleukin-6Interleukin-8Lipoproteins, LDLoxidized low density lipoproteinTumor Necrosis Factor-alphaHIVinflammationinsulin resistancemonocytes

Identifiers

PMID33028018
PMCPMC7601436
OpenAlexW3089642717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.