Evidence map›Paper›PMID 33027942›Full record

ArticleJournal of clinical medicine2020

Polyphenol Bioavailability and Plasma Antiradical Capacity in Healthy Subjects after Acute Intake of Pigmented Rice: A Crossover Randomized Controlled Clinical Trial.

Sara Vitalini, Andrea Sardella, Daniela Fracassetti, Rita Secli, Antonio Tirelli, Giovanni Lodi, Antonio Carrassi, Elena Maria Varoni, Marcello Iriti

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Article
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sara VitaliniDepartment of Agricultural and Environmental Sciences, Università degli Studi di Milano, 20133 Milan, Italy.
Andrea SardellaDepartment of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, 20142 Milan, Italy.ORCID 0000-0003-4491-4640
Daniela FracassettiDepartment of Food, Environmental and Nutritional Sciences, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0003-0525-7123
Rita SecliASST Santi Paolo e Carlo-Presidio Ospedaliero San Paolo-Università degli Studi di Milano, 20142 Milan, Italy.
Antonio TirelliDepartment of Food, Environmental and Nutritional Sciences, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0001-9108-8906
Giovanni LodiDepartment of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, 20142 Milan, Italy.
Antonio CarrassiDepartment of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, 20142 Milan, Italy.
Elena Maria VaroniDepartment of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, 20142 Milan, Italy.ORCID 0000-0002-7287-2188
Marcello IritiDepartment of Agricultural and Environmental Sciences, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0002-5063-1236
University of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Health-promoting effects of plant foods have been emphasized in the last few decades and ascribed to the bioactive phytochemicals present therein-in particular, phenylpropanoids. The latter have been investigated for a number of preclinical biological activities, including their antioxidant power. Due to the paucity of human studies, in this randomized intervention trial, we investigated whether the acute intake of pigmented rice could increase the plasma bioactive levels and antiradical power in twenty healthy subjects. A crossover randomized controlled clinical trial was conducted on 19 volunteers. Artemide and Venere black rice cultivars were tested, while brown rice Carnaroli was used as a control. Each patient received randomly one serving (100 g) of rice on three different experimental days, separated by a 7-day washout period. After baseline blood withdrawal, time-course changes of plasma polyphenols, flavonoids and radical-scavenging capacity were determined at 30, 60, 120 and 180 min post rice intake. Compared to Carnaroli rice, the two black rice cultivars significantly increased the plasma levels of polyphenols and flavonoids at 60 and 120 min and, correspondingly, the plasma antiradical power at 60 min after consumption. Pigmented rice consumption can contribute to diet-related health benefits in humans.

Indexed as

anthocyaninsantioxidant activityblack rice cultivarscerealsflavonoids

Identifiers

PMID33027942
PMCPMC7601283
OpenAlexW3090618159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.