Evidence map›Paper›PMID 33027935›Full record

ArticleNanomaterials (Basel, Switzerland)2020

Synergistic Effect of Chitosan and Selenium Nanoparticles on Biodegradation and Antibacterial Properties of Collagenous Scaffolds Designed for Infected Burn Wounds.

Jana Dorazilová, Johana Muchová, Kristýna Šmerková, Silvia Kočiová, Pavel Diviš, Pavel Kopel, Radek Veselý, Veronika Pavliňáková, Vojtěch Adam, Lucy Vojtová

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. A review of new developments in peripheral nerve regeneration.Biochemistry and biophysics reports · 2026
    Review
  2. Article
  3. ACS omega · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Application of chitosan-based nanoparticles in skin wound healing.Asian journal of pharmaceutical sciences · 2022
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jana DorazilováCEITEC-Central European Institute of Technology, Brno University of Technology, Purkyňova 656/123, 612 00 Brno, Czech Republic.ORCID 0000-0002-4072-8173
Johana MuchováCEITEC-Central European Institute of Technology, Brno University of Technology, Purkyňova 656/123, 612 00 Brno, Czech Republic.
Kristýna ŠmerkováCEITEC-Central European Institute of Technology, Brno University of Technology, Purkyňova 656/123, 612 00 Brno, Czech Republic.
Silvia KočiováCEITEC-Central European Institute of Technology, Brno University of Technology, Purkyňova 656/123, 612 00 Brno, Czech Republic.
Pavel DivišFaculty of Chemistry, Brno University of Technology, Purkyňova 118, 612 00 Brno, Czech Republic.
Pavel KopelCEITEC-Central European Institute of Technology, Brno University of Technology, Purkyňova 656/123, 612 00 Brno, Czech Republic.ORCID 0000-0003-4216-9544
Radek VeselýDepartment of Traumatology at the Medical Faculty, Masaryk University and Trauma Hospital of Brno, Ponavka 6, 662 50 Brno, Czech Republic.
Veronika PavliňákováCEITEC-Central European Institute of Technology, Brno University of Technology, Purkyňova 656/123, 612 00 Brno, Czech Republic.
Vojtěch AdamCEITEC-Central European Institute of Technology, Brno University of Technology, Purkyňova 656/123, 612 00 Brno, Czech Republic.
Lucy VojtováCEITEC-Central European Institute of Technology, Brno University of Technology, Purkyňova 656/123, 612 00 Brno, Czech Republic.

Funding

Agentura Pro Zdravotnický Výzkum České Republiky AZV 17-29874AEuropean Regional Development Fund CZ.02.1.01/0.0/0.0/16_025/0007314National Sustainability Program II, Ministry of Education, Youth and Sports LQ1601Specific Research Project of the Brno University of Technology CEITEC VUT-J-19-6086
6 · The paper itself

Abstract

A highly porous scaffold is a desirable outcome in the field of tissue engineering. The porous structure mediates water-retaining properties that ensure good nutrient transportation as well as creates a suitable environment for cells. In this study, porous antibacterial collagenous scaffolds containing chitosan and selenium nanoparticles (SeNPs) as antibacterial agents were studied. The addition of antibacterial agents increased the application potential of the material for infected and chronic wounds. The morphology, swelling, biodegradation, and antibacterial activity of collagen-based scaffolds were characterized systematically to investigate the overall impact of the antibacterial additives. The additives visibly influenced the morphology, water‑retaining properties as well as the stability of the materials in the presence of collagenase enzymes. Even at concentrations as low as 5 ppm of SeNPs, modified polymeric scaffolds showed considerable inhibition activity towards Gram-positive bacterial strains such as

Indexed as

bacteriachitosancollagendrug releasefreeze-dryinginfected burn injuriesselenium nanoparticlesStaphylococcustissue engineering

Identifiers

PMID33027935
PMCPMC7601368

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.