Evidence map›Paper›PMID 33027894›Full record

ArticleInternational journal of molecular sciences2020

Total Blood Exosomes in Breast Cancer: Potential Role in Crucial Steps of Tumorigenesis.

Maria Konoshenko, Georgy Sagaradze, Evgeniya Orlova, Tatiana Shtam, Ksenia Proskura, Roman Kamyshinsky, Natalia Yunusova, Antonina Alexandrova, Anastasia Efimenko, Svetlana Tamkovich

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  7. Exosomal Cargo in Ovarian Cancer Dissemination.Current issues in molecular biology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Maria KonoshenkoInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Georgy SagaradzeMedical Research and Education Center, Lomonosov Moscow State University, 119991 Moscow, Russia.
Evgeniya OrlovaN.N. Blokhin Cancer Research Center" of the Ministry of Health of the Russian Federation, 115478 Moscow, Russia.
Tatiana ShtamPetersburg Nuclear Physics Institute named by B.P. Konstantinov of National Research Center "Kurchatov Institute", 188300 Gatchina, Russia.ORCID 0000-0003-0651-4785
Ksenia ProskuraInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Roman KamyshinskyNational Research Center "Kurchatov Institute", 123182 Moscow, Russia.ORCID 0000-0002-8546-7763
Natalia YunusovaCancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Science, 634050 Tomsk, Russia.
Antonina AlexandrovaN.N. Blokhin Cancer Research Center" of the Ministry of Health of the Russian Federation, 115478 Moscow, Russia.
Anastasia EfimenkoMedical Research and Education Center, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0002-0696-1369
Svetlana TamkovichInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0001-7774-943X
Institute of Chemical Biology and Fundamental Medicine · RULomonosov Moscow State University · RURussian Cancer Research Center NN Blokhin · RUKurchatov Institute · RUNovosibirsk State University · RURussian Academy of Sciences · RUSiberian State Medical University · RU

Funding

Russian Foundation for Basic Research 18-015-00289Russian Foundation for Basic Research 18-54-16006Russian Science Foundation 19-74-20146Russian Science Support Foundation 16-15-10288
6 · The paper itself

Abstract

Exosomes are crucial players in cell-to-cell communication and are involved in tumorigenesis. There are two fractions of blood circulating exosomes: free and cell-surface-associated. Here, we compared the effect of total blood exosomes (contain plasma exosomes and blood cell-surface-associated exosomes) and plasma exosomes from breast cancer patients (BCPs,

Indexed as

AdultAgedBiomarkers, TumorBreastBreast NeoplasmsCarcinogenesisCell MovementCell ProliferationCryoelectron MicroscopyEpithelial-Mesenchymal TransitionExosomesFemaleGene Expression Regulation, NeoplasticHumansMicroRNAsMiddle AgedBiomarkers, TumorMicroRNAsangiogenesisbreast cancercryo-electron microscopyexosomesmicroRNAsmigration

Identifiers

PMID33027894
PMCPMC7582945
OpenAlexW3090980144

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.