Evidence map›Paper›PMID 33027886›Full record

ReviewJournal of clinical medicine2020

Hypercapnia: An Aggravating Factor in Asthma.

Masahiko Shigemura, Tetsuya Homma, Jacob I Sznajder

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Predictive correlates of poor sleep associated with increased risk of severe asthma exacerbations among children with moderate-to-severe asthma.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Elevated COInterface focus · 2021
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Masahiko ShigemuraDivision of Pulmonary and Critical Care Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0001-7767-6584
Tetsuya HommaDepartment of Allergology and Respiratory Medicine, University of Showa School of Medicine, Tokyo 142-0064, Japan.
Jacob I SznajderDivision of Pulmonary and Critical Care Medicine, Northwestern University, Chicago, IL 60611, USA.
Northwestern University · USShowa University · JP

Funding

Role of hypercapnia on the lung airwaysR01HL147070 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SZNAJDER, JACOB I · 2019 to 2022
$1.9M
NHLBI NIH HHS R01 HL147070NIH HHS HL-147070
6 · The paper itself

Abstract

Asthma is a common chronic respiratory disorder with relatively good outcomes in the majority of patients with appropriate maintenance therapy. However, in a small minority, patients can experience severe asthma with respiratory failure and hypercapnia, necessitating intensive care unit admission. Hypercapnia occurs due to alveolar hypoventilation and insufficient removal of carbon dioxide (CO

Indexed as

airway contractilityasthmahypercapniainnate immune responseobesityrespiratory failure

Identifiers

PMID33027886
PMCPMC7599850
OpenAlexW3091728228

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.