Evidence map›Paper›PMID 33027842›Full record

ArticleInternational journal of geriatric psychiatry2021

Challenging the relationship of grip strength with cognitive status in older adults.

Andrew Hooyman, Michael Malek-Ahmadi, Elizabeth B Fauth, Sydney Y Schaefer

Abstract read
In one paragraph

Article in International journal of geriatric psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. A sensorimotor function construct to assess mild cognitive impairment risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  2. Comparing Demographic Effects on Current and Novel Neuropsychological Measures in Older Adults with and without Alzheimer's Disease.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025
    Article
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  10. Contribution of Home Gardens to Sustainable Development: Perspectives from A Supported Opinion Essay.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrew HooymanSchool of Biological and Health Systems Engineering, Arizona State University, Tempe, Arizona, USA.
Michael Malek-AhmadiBanner Alzheimer's Institute, Phoenix, Arizona, USA.
Elizabeth B FauthDepartment of Human Development and Family Studies, Utah State University, Logan, Utah, USA.ORCID 0000-0002-4009-0560
Sydney Y SchaeferSchool of Biological and Health Systems Engineering, Arizona State University, Tempe, Arizona, USA.ORCID 0000-0002-6976-8419

Funding

Generalization of functional task-specific motor training in older adultsK01AG047926 · NIA · UTAH STATE UNIVERSITY · PI SCHAEFER, SYDNEY YOSHIE · 2015 to 2018
$543k
NIA NIH HHS K01 AG047926
6 · The paper itself

Abstract

objectiveGrip strength is a widely used motor assessment in ageing research and has repeatedly been shown to be associated with cognition. It has been proposed that grip strength could enhance cognitive screening in experimental or clinical research, but this study uses multiple data-driven approaches to caution against this interpretation. Furthermore, we introduce an alternative motor assessment, comparable to grip dynamometry, but has a more robust relationship with cognition among older adults.

designAssociations between grip strength and cognition (measured with the Montreal Cognitive Assessment) were analysed cross sectionally using multivariate regression in two datasets: (1) The Irish LongituDinal Study on Ageing (TILDA; N = 5,980, community-dwelling adults ages 49-80) and (2) an experimental dataset (N = 250, community-dwelling adults aged 39-98). Additional statistical simulations on TILDA tested how ceiling effects or skewness in these variables influenced these associations for quality control.

resultsGrip strength was significantly but weakly associated with cognition, consistent with previous studies. Simulations revealed this was not due to skewness/ceiling effects. Conversely, a new alternative motor assessment (functional reaching [FR]) had a stronger, more robust and more sensitive relationship with cognition compared to grip strength.

conclusionsGrip strength should be cautiously interpreted as being associated with cognition. However, FR may have a stronger and clinically useful relationship with cognition.

Indexed as

AgingHand StrengthAgedAged, 80 and overCognitionCross-Sectional StudiesHumansIndependent LivingLongitudinal Studiescognitiondata simulationgrip strengthphysical function

Identifiers

PMID33027842
PMCPMC13317022

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.