Evidence map›Paper›PMID 33027670›Full record

ArticleCell metabolism2020

Getting Warmer: Following One's Gut to Build Bone.

Jameel Iqbal, Tony Yuen, Mone Zaidi

Open access · bronzeAbstract readComment
In one paragraph

Article in Cell metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jameel IqbalMount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pathology, James J. Peters VA Medical Center, Bronx, NY 10463, USA.
Tony YuenMount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Mone ZaidiMount Sinai Bone Program, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: mone.zaidi@mssm.edu.
Icahn School of Medicine at Mount Sinai · USMount Sinai Medical Center · US

Funding

Targeting FSH for the Therapy of Osteoporosis, Obesity and NeurodegenerationU19AG060917 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI PENG LIU · 2019 to 2026
$29.0M
Thyrotropin Receptor, Thyrotropin and Mechanisms of Bone LossR01DK113627 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI DAVIES, TERRY FRANCIS, IQBAL, JAMEEL Z · 2017 to 2020
$2.8M
NIA NIH HHS U19 AG060917NIDDK NIH HHS R01 DK113627
6 · The paper itself

Abstract

In this issue of the Cell Metabolism, Chevalier et al. show that a warm environment produces changes in the composition of intestinal microbiota and that these changes can prevent bone loss due to hypogonadism. Dovetailing with prior studies on the ability of probiotics to reverse hypogonadism-induced osteopenia, the findings reaffirm a central role for the microbiome in regulating bone mass in response to both environmental and hormonal cues.

Indexed as

Bone Diseases, MetabolicGastrointestinal MicrobiomeMicrobiotaProbioticsHumans

Identifiers

PMID33027670
PMCPMC11658026
OpenAlexW3092630515

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.