Evidence map›Paper›PMID 33027081›Full record

ArticleThe American journal of gastroenterology2021

Empagliflozin Eliminates Refractory Ascites and Hepatic Hydrothorax in a Patient With Primary Biliary Cirrhosis.

Georgios N Kalambokis, Ilias Tsiakas, Sebastien Filippas-Ntekuan, Maria Christaki, Grigorios Despotis, Haralampos Milionis

Registry-linked trialAbstract readCase Reports
PubMed Publisher
In one paragraph

Article in The American journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05999773 (Potential Role of Sodium Glucose Cotransporter 2 Inhibitors in the Treatment of Ascites in Cirrhotic Patients), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05999773 active not recruitingstarted 2023, after this paper: background citation

Potential Role of Sodium Glucose Cotransporter 2 Inhibitors in the Treatment of Ascites in Cirrhotic Patients

Ran2023Enrolled40Registered outcomes18Posted comparisons0ConditionsAscites Hepatic, Cirrhosis, Liver, Diabete Type 2ArmsSGLT2 inhibitor
Open the trial in the graph
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Role of sodium-glucose cotransporter 2 inhibitors in liver diseases.World journal of experimental medicine · 2025
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Innovative approaches to the management of ascites in cirrhosis.JHEP reports : innovation in hepatology · 2023
    Review
  16. Review
  17. Review
  18. Article
  19. SGLT2 Inhibitors: A New Dawn for Recurrent/Refractory Cirrhotic Ascites.Journal of clinical and translational hepatology · 2021 · on this map
    Article
  20. Management of Portal Hypertension.Journal of clinical and experimental hepatology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Georgios N Kalambokis1st Department of Internal Medicine, School of Medicine, University of Ioannina, Ioannina, Greece.
Ilias Tsiakas
Sebastien Filippas-Ntekuan
Maria Christaki
Grigorios Despotis
Haralampos Milionis
University of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AscitesBenzhydryl CompoundsDiabetes Mellitus, Type 2FemaleGlucosidesHumansHydrothoraxLiver Cirrhosis, BiliaryMiddle AgedSodium-Glucose Transporter 2 InhibitorsTreatment OutcomeBenzhydryl CompoundsempagliflozinGlucosidesSodium-Glucose Transporter 2 Inhibitors

Identifiers

PMID33027081
OpenAlexW3092534644

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.