ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2020
Prospective Cohort Study of Pre- and Postdiagnosis Physical Activity and Endometrial Cancer Survival.
Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT03422198 (Short Course Adjuvant Vaginal Cuff Brachytherapy), which is not on this map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Short Course Adjuvant Vaginal Cuff Brachytherapy (VCB) in Early Endometrial Cancer Compared to Standard of Care (SAVE)
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Post-diagnosis physical activity in relation to mortality among gynecological cancer survivors.Cancer causes & control : CCC · 2026Pooled it
- Long-Term Engagement With a Physical Activity App Among Gynecologic Cancer Survivors in the LETSGO Trial: 12-Month Prospective, Multicenter, Quasi-Experimental Study.JMIR mHealth and uHealth · 2026Trial
- Experiences and facilitators of physical activity engagement amongst colorectal and endometrial cancer survivors: the Wearable Activity Technology and Action-Planning (WATAAP) trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Trial
- ENhAncing Lifestyle Behaviors in EndometriaL CancEr (ENABLE): A Pilot Randomized Controlled Trial.Integrative cancer therapiesTrial
- Lung Cancer Survivorship: Challenges and Care Needs.Cancers · 2026Review
- Long-term association of physical activity with survival by primary cancer treatment in endometrial cancer: The Alberta Endometrial Cancer Cohort Study.International journal of cancer · 2026Article
- Physical activity across the life course and neural biomarkers.Journal of Alzheimer's disease : JAD · 2026Article
- Fats and Facts: A Meta-Analysis of Lipid Biomarkers in Endometrial Cancer.Life (Basel, Switzerland) · 2026Review
- Leisure-Time Physical Activity and Cancer Mortality Among Cancer Survivors.JAMA network open · 2026Article
- Every move matters: physical activity, walking, sedentary behavior, and endometrial cancer survival.Cancer causes & control : CCC · 2025Article
- Physical activity interventions in women treated for endometrial cancer: a scoping review.Journal of cancer survivorship : research and practice · 2025Review
- Leisure-time physical activity after diagnosis and survival by cancer type: a pooled analysis.Journal of the National Cancer Institute · 2025Article
- Molecular, cellular, biochemical, and rehabilitative insights into exercise interventions for gynecological cancer prevention and survivorship: a narrative review.Journal of ovarian research · 2025Review
- Cancer prognosis and treatment results in patients with PTEN Hamartoma Tumour Syndrome (PHTS)-a European cohort study.BJC reports · 2025Article
- Wearable device-measured physical activity and incident cardiovascular disease in cancer survivors.British journal of sports medicine · 2025Article
- Physical Activity and Cancer Incidence and Mortality: Current Evidence and Biological Mechanisms.Cancers · 2025Review
- Personalized Lifestyle Interventions for Prevention and Treatment of Obesity-Related Cancers: A Call to Action.Cancers · 2025Article
- Causal relationship between physical activity and common gynecologic conditions: a two-sample Mendelian randomization study.American journal of translational research · 2025Article
- Editorial: Promotion of quality of life in oncology patients and survivors through physical activity.Frontiers in oncology · 2025Article
- Exercise Across the Phases of Cancer Survivorship: A Narrative Review.Yonsei medical journal · 2024Review
Corrections and comments
- Erratum issuedErratum.2021
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
purposeThe aim of this study was to evaluate associations between pre- and postdiagnosis physical activity and survival in survivors of endometrial cancer by physical activity domain, intensity, dose (metabolic-equivalent task [MET]-hours/week/year), and change from pre- to postdiagnosis.
methodsWe conducted a prospective cohort study in Alberta, Canada, of 425 women who were diagnosed with histologically confirmed invasive endometrial cancer between 2002 and 2006 and observed to 2019. The interviewer-administered Lifetime Total Physical Activity Questionnaire recorded prediagnosis (assessed at a median of 4.4 months after diagnosis) and postdiagnosis physical activity (assessed at a median of 3.4 years after diagnosis). Associations between physical activity and overall and disease-free survival were assessed using Cox proportional hazards models adjusted for age, stage, grade, treatments, body mass index, menopausal status, hormone therapy use, family history of cancer, and comorbidities.
resultsAfter a median follow-up of 14.5 years, there were 60 deaths, including 18 endometrial cancer deaths, and 80 disease-free survival events. Higher prediagnosis recreational physical activity was statistically significantly associated with improved disease-free survival (> 14
conclusionRecreational physical activity, especially postdiagnosis, is associated with improved survival in survivors of endometrial cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.