ArticleArthritis care & research2021
Cumulative Disadvantage and Disparities in Depression and Pain Among Veterans With Osteoarthritis: The Role of Perceived Discrimination.
Article in Arthritis care & research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06493903 (Physical and Mental Health Intervention for Black Adults With Knee Osteoarthritis), which is not on this map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Physical and Mental Health Intervention for Black Adults With Knee Osteoarthritis: A Feasibility Study
Who cites it
20 citing papers in PubMed, 35 citations in OpenAlex.
- Emotional Awareness and Expression Therapy vs Cognitive Behavioral Therapy for Chronic Pain in Older Veterans: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Relationship Between Social Vulnerability Indicators and Trial Participant Attrition: Findings From the HYVALUE Trial.Circulation. Cardiovascular quality and outcomes · 2022Trial
- Racial Differences in Utilization of and Factors Contributing to the Use of Knee Replacement Surgery as a Treatment for Severe Knee Osteoarthritis: A Scoping Review.Osteoarthritis and cartilage open · 2026Review
- Opioid Prescriptions for Low Back Pain among Military-Connected Older Adults Across Multiple Care Systems.Drugs & aging · 2025Article
- An application of the biopsychosocial model for pain in Canadian Veterans Life After Service Studies 2019 survey.Journal of military, veteran and family health · 2024Article
- Telehealth delivery of physical therapist-led interventions for persons with chronic low back pain in underserved communities: lessons from pragmatic clinical trials.Frontiers in pain research (Lausanne, Switzerland) · 2024Article
- Barriers to accessing pain management services among veterans with bipolar disorder.Health services research · 2023Article
- The impact of ethnic discrimination on chronic pain: the role of sex and depression.Ethnicity & health · 2023Article
- Racial and Ethnic Disparities in the Incidence of High-Impact Chronic Pain Among Primary Care Patients with Acute Low Back Pain: A Cohort Study.Pain medicine (Malden, Mass.) · 2023Article
- Researchers in rheumatology should avoid categorization of continuous predictor variables.BMC medical research methodology · 2023Article
- Understanding the Context for Incorporating Equity into Quality Improvement Throughout a National Health Care System.Health equity · 2023Article
- Article
- Disease-Specific Health Disparities: A Targeted Review Focusing on Race and Ethnicity.Healthcare (Basel, Switzerland) · 2022Review
- Applying the NIA Health Disparities Research Framework to Identify Needs and Opportunities in Chronic Musculoskeletal Pain Research.The journal of pain · 2022Review
- Roles of Hormone Replacement Therapy and Menopause on Osteoarthritis and Cardiovascular Disease Outcomes: A Narrative Review.Frontiers in rehabilitation sciences · 2022Review
- Depression in Osteoarthritis: Current Understanding.Neuropsychiatric disease and treatment · 2022Review
- Network Analysis of Time Use and Depressive Symptoms Among Emerging Adults: Findings From the Guizhou Population Health Cohort Study.Frontiers in psychiatry · 2022Article
- Race Differences in Resilience Among Older Adults with Chronic Low Back Pain.Journal of pain research · 2021Article
- Article
- A historical review of pain disparities research: Advancing toward health equity and empowerment.Nursing outlookReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
objectivePerceived discrimination is associated with chronic pain and depression and contributes to racial health disparities. In a cohort of older adult veterans with osteoarthritis (OA), our objective was to examine how membership in multiple socially disadvantaged groups (cumulative disadvantage) was associated with perceived discrimination, pain, and depression. We also tested whether perceived discrimination mediated the association of cumulative disadvantage with depression and pain.
methodsWe analyzed baseline data from 270 African American veterans and 247 White veterans enrolled in a randomized controlled trial testing a psychological intervention for chronic pain at 2 Department of Veterans Affairs medical centers. Participants were age ≥50 years and self-reported symptomatic knee OA. Measures included the Everyday Discrimination Scale, the Patient Health Questionnaire Depression Scale, the Western Ontario and McMaster Universities Osteoarthritis Index pain subscale, and demographic variables. Cumulative disadvantage was defined as the number of socially disadvantaged groups to which each participant belonged (i.e., self-reported female sex, African American race, annual income of <$20,000, and/or unemployed due to disability). We used linear regression models and Sobel's test of mediation to examine hypotheses.
resultsThe mean ± SD number of social disadvantages was 1.3 ± 1.0. Cumulative disadvantage was significantly associated with higher perceived discrimination, pain, and depression (P < 0.001 for all). Perceived discrimination significantly mediated the association between cumulative disadvantage and depression symptoms (Z = 3.75, P < 0.001) as well as pain severity (Z = 2.24, P = 0.025).
conclusionPerceived discrimination is an important psychosocial stressor that contributes to worsening OA-related mental and physical health outcomes, with greater effects among those from multiple socially disadvantaged groups.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.