ArticleArthritis care & research2022
Association of Quadriceps Strength Symmetry and Surgical Status With Clinical Osteoarthritis Five Years After Anterior Cruciate Ligament Rupture.
Article in Arthritis care & research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05131048 (Effects of Home-based Hip Strengthening Exercises on Pain, Range of Motion and Functional Disability in Knee Osteoarthritis Patients), which is not on this map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Home-based Hip Strengthening Exercises on Pain, Range of Motion and Functional Disability in Knee Osteoarthritis Patients: a Randomized Controlled Trial
Who cites it
35 citing papers in PubMed, 48 citations in OpenAlex.
- The effect of incorporating whole body vibration into exercise therapy on the corticomotor excitability of the quadriceps in athletes following anterior cruciate ligament reconstruction.Scientific reports · 2025Trial
- Reconstruction After an Anterior Cruciate Ligament Injury Does Not Reduce the Osteoarthritis Risk But Lowers the Total Knee Arthroplasty Rate: A Systematic Review and Meta-analysis.Orthopaedic journal of sports medicine · 2026Review
- Midterm Quadriceps Strength Outcomes of Revision ACL Reconstructions Comparing Ipsilateral Extensor Mechanism Autografts and Hamstring Tendon Autografts.Orthopaedic journal of sports medicine · 2026Article
- Asymmetrical biomechanics in knee osteoarthritis: a review of contralateral risk from primary disease to post-arthroplasty progression.EFORT open reviews · 2026Review
- Isokinetic Quadriceps and Hamstring Peak Torque in Athletes Aged 10-50+: Preoperative Uninvolved Limb Reference Values for ACL Reconstruction.International journal of sports physical therapy · 2026Article
- Preoperative systemic inflammation and muscle fatty infiltration are prognostic factors for quadriceps atrophy following anterior cruciate ligament reconstruction.Frontiers in immunology · 2026Article
- CSF1-R inhibition attenuates posttraumatic osteoarthritis and quadriceps atrophy following ligament injury.The Journal of physiology · 2025Article
- Relationship between Changes in Physical Activity and Knee Health 18 Months after ACL Reconstruction.Medicine and science in sports and exercise · 2025Article
- No difference in ACL revision rates between hamstring and patellar tendon autograft in patients with ACL-R and a concurrent meniscal injury irrespective of meniscal treatment.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
- Shear wave elastography reveals elevated infrapatellar fat pad stiffness in patients with early osteoarthritis symptoms after ACL reconstruction.Osteoarthritis imaging · 2025Article
- Clinical, Functional, Sports Participation, and Osteoarthritis Outcomes After ACL Injury: Ten-Year Follow-up Study of the Delaware-Oslo ACL Cohort Treatment Algorithm.The Journal of bone and joint surgery. American volume · 2025Article
- Evaluating Criteria for Symptoms Suggestive of Early Osteoarthritis Over Two Years Post-Anterior Cruciate Ligament Reconstruction: Data From the New Zealand Anterior Cruciate Ligament Registry.Arthritis care & research · 2025Article
- Symptoms indicative of early knee osteoarthritis after ACL reconstruction: descriptive analysis of the SHIELD cohort.Osteoarthritis and cartilage open · 2025Article
- Quadriceps-Strength-Testing Practices and Barriers During Return to Sport After ACL Reconstruction: A Survey of College Athletic Trainers.Journal of athletic training · 2025Article
- Social Determinants of Health and Quadriceps Strength Recovery in Children and Adolescents following Anterior Cruciate Ligament Reconstruction.International journal of sports physical therapy · 2025Article
- Sedentary Behavior Patterns After ACL Reconstruction.International journal of exercise science · 2025Article
- Quadriceps tendon size does not affect postoperative strength recovery following quadriceps tendon anterior cruciate ligament reconstruction.Journal of ISAKOS : joint disorders & orthopaedic sports medicine · 2024Article
- Persistent Early Knee Osteoarthritis Symptoms From 6 to 12 Months After Anterior Cruciate Ligament Reconstruction.Journal of athletic training · 2024Article
- Prolonged quadriceps latency during gait early after anterior cruciate ligament injury predicts radiographic knee osteoarthritis 6-years after anterior cruciate ligament reconstruction.Clinical biomechanics (Bristol, Avon) · 2024Article
- Knee Extensor Torque Steadiness and Quadriceps Activation Variability in Collegiate Athletes 4, 6, and 12 Months After ACL Reconstruction.Orthopaedic journal of sports medicine · 2024Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 3 countries.
Funding
Abstract
objectiveThe objective of this study was to examine the association of quadriceps strength symmetry and surgical status (anterior cruciate ligament [ACL] reconstruction or nonoperative management) with early clinical knee osteoarthritis (OA) 5 years after ACL injury or reconstruction.
methodsIn total, 204 of 300 athletes were analyzed 5 years after ACL injury or reconstruction. Quadriceps strength was measured and reported as a limb symmetry index. We identified participants with early clinical knee OA using the criteria that 2 of 4 Knee Injury and Osteoarthritis Outcome Score (KOOS) subscales score ≤85%. We calculated odds ratios (ORs) and 95% confidence intervals (95% CIs) using logistic regression and adjusted for age, sex, meniscal injury, and body mass index to examine the associations of quadriceps strength and surgical status with clinical knee OA.
resultsIn all, 21% of participants met the KOOS criteria for clinical knee OA. For every 1% increase in quadriceps limb symmetry index, there was a 4% lower odds of clinical OA (adjusted OR [OR
conclusionMore symmetric quadriceps strength, but not surgical status, 5 years after ACL injury or reconstruction was associated with lower odds of clinical knee OA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.