ArticleeLife2020
Cerebellar patients have intact feedback control that can be leveraged to improve reaching.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Who cites it
20 citing papers in PubMed.
- Sensorimotor Adaptation of Vocal Pitch Is Impaired in Cerebellar Ataxia.Journal of cognitive neuroscience · 2026Article
- Pretraining of Embodied Recurrent Networks Bridges the Gap Between Artificial and Cortical Neural Activities.Biomimetics (Basel, Switzerland) · 2026Article
- Modeling framework disentangles cerebellar mechanisms in speech feedback control, revealing trade-offs reshaped by degeneration.bioRxiv : the preprint server for biology · 2026Article
- Cerebellar contributions to action and cognition: Prediction, timescale, and continuity.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Sensorimotor adaptation of vocal pitch is severely impaired in cerebellar ataxia.bioRxiv : the preprint server for biology · 2025Article
- Cerebellar circuit computations for predictive motor control.Nature reviews. Neuroscience · 2025Review
- Cerebellar reaching ataxia is exacerbated by timing demands and assistive interaction torques.Scientific reports · 2025Article
- The control of movement gradually transitions from feedback control to feedforward adaptation throughout childhood.NPJ science of learning · 2025Article
- Feedback and feedforward control are differentially delayed in cerebellar ataxia.bioRxiv : the preprint server for biology · 2025Article
- Bayesian inference of state feedback control parameters for fo perturbation responses in cerebellar ataxia.PLoS computational biology · 2024Article
- Reinforcement Motor Learning After Cerebellar Damage Is Related to State Estimation.Cerebellum (London, England) · 2024Article
- Preliminary Study of Vibrotactile Feedback during Home-Based Balance and Coordination Training in Individuals with Cerebellar Ataxia.Sensors (Basel, Switzerland) · 2022Article
- Differential Effects of Cerebellar Degeneration on Feedforward versus Feedback Control across Speech and Reaching Movements.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Article
- Intact Correction for Self-Produced Vowel Formant Variability in Individuals With Cerebellar Ataxia Regardless of Auditory Feedback Availability.Journal of speech, language, and hearing research : JSLHR · 2021Article
- Reinforcement Signaling Can Be Used to Reduce Elements of Cerebellar Reaching Ataxia.Cerebellum (London, England) · 2021Article
- The Forward Model: A Unifying Theory for the Role of the Cerebellum in Motor Control and Sense of Agency.Frontiers in systems neuroscience · 2021Article
- Article
- The Cerebellar Nuclei and Dexterous Limb Movements.Neuroscience · 2020Review
- Cerebellar patients have intact feedback control that can be leveraged to improve reaching.eLife · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
It is thought that the brain does not simply react to sensory feedback, but rather uses an internal model of the body to predict the consequences of motor commands before sensory feedback arrives. Time-delayed sensory feedback can then be used to correct for the unexpected-perturbations, motor noise, or a moving target. The cerebellum has been implicated in this predictive control process. Here, we show that the feedback gain in patients with cerebellar ataxia matches that of healthy subjects, but that patients exhibit substantially more phase lag. This difference is captured by a computational model incorporating a Smith predictor in healthy subjects that is missing in patients, supporting the predictive role of the cerebellum in feedback control. Lastly, we improve cerebellar patients' movement control by altering (phase advancing) the visual feedback they receive from their own self movement in a simplified virtual reality setup.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.