Article in Synapse (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
8 authors at 1 institution in 1 country.
Carolina Burgos-AguilarDepartment of Physiology and Pharmacology, Center for the Neurobiology of Addiction Treatment, One Medical Center Blvd., Wake Forest School of Medicine, Winston-Salem, NC, USA.ORCID 0000-0002-7364-1402
Mark J FerrisDepartment of Physiology and Pharmacology, Center for the Neurobiology of Addiction Treatment, One Medical Center Blvd., Wake Forest School of Medicine, Winston-Salem, NC, USA.
Lacey L SextonDepartment of Physiology and Pharmacology, Center for the Neurobiology of Addiction Treatment, One Medical Center Blvd., Wake Forest School of Medicine, Winston-Salem, NC, USA.
Haiguo SunDepartment of Physiology and Pharmacology, Center for the Neurobiology of Addiction Treatment, One Medical Center Blvd., Wake Forest School of Medicine, Winston-Salem, NC, USA.
Ruoyu XiaoDepartment of Physiology and Pharmacology, Center for the Neurobiology of Addiction Treatment, One Medical Center Blvd., Wake Forest School of Medicine, Winston-Salem, NC, USA.
Rong ChenDepartment of Physiology and Pharmacology, Center for the Neurobiology of Addiction Treatment, One Medical Center Blvd., Wake Forest School of Medicine, Winston-Salem, NC, USA.
Steven R ChildersDepartment of Physiology and Pharmacology, Center for the Neurobiology of Addiction Treatment, One Medical Center Blvd., Wake Forest School of Medicine, Winston-Salem, NC, USA.
Allyn C HowlettDepartment of Physiology and Pharmacology, Center for the Neurobiology of Addiction Treatment, One Medical Center Blvd., Wake Forest School of Medicine, Winston-Salem, NC, USA.ORCID 0000-0002-2810-0164
Wake Forest University · US
Funding
TROPANE EVALUATION AND GENERAL SCIENTIFIC SERVICES COREP50DA006634 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HOWLETT, ALLYN C · 1991 to 2019
$30.8M
Cannabinoid Receptors and Associated Proteins-RenewalR01DA042157 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ALLYN C HOWLETT, W TODD LOWTHER · 2017 to 2026
$5.4M
RGS2 regulation of D2 receptor signalingR01DA042862 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CHEN, RONG · 2017 to 2021
Metabotropic glutamate (mGlu) receptors are regulators of glutamate release and targets for development of therapies for hyperactive glutamatergic signaling. However, the effects of long-term stimulation of mGlu receptors on cellular signaling in the brain have not been described. This study investigated the effects of 2-day and 14-day osmotic mini-pump administration of the mGlu2,3 agonist LY379268 (3.0 mg kg
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Metabotropic glutamate 2,3 receptor stimulation desensitizes agonist activation of G-protein signaling and alters transcription regulators in mesocorticolimbic brain regions. · full record | OpenQuestion