Evidence map›Paper›PMID 33025519›Full record

ArticleBiological trace element research2021

Association Between Selenium Level in Blood and Glycolipid Metabolism in Residents of Enshi Prefecture, China.

Haiqin Fang, Xiaohong He, Yingyu Wu, Siqiang Chen, Mingyuan Zhang, Feng Pan, Jiao Huang, Aidong Liu

Abstract read
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. A Functional Variant inFrontiers in nutrition · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Haiqin Fang *China National Center for Food Safety Risk Assessment, Beijing, 100021, China.
Xiaohong He *Enshi Center for Disease Control and Prevention, Enshi, 445000, Hubei, China.
Yingyu Wu *College of Agricultural and Environmental Sciences, United States, University of California, Davis, CA, USA.
Siqiang ChenEnshi Center for Disease Control and Prevention, Enshi, 445000, Hubei, China.
Mingyuan ZhangChina National Center for Food Safety Risk Assessment, Beijing, 100021, China.
Feng PanChina National Center for Food Safety Risk Assessment, Beijing, 100021, China.
Jiao HuangSchool of Public Health, Huazhong, Huazhong University of Science and Technology, Wuhan, China.
Aidong LiuChina National Center for Food Safety Risk Assessment, Beijing, 100021, China. liuaidong@cfsa.net.cn.ORCID http://orcid.org/0000-0002-4987-7888
China National Center for Food Safety Risk Assessment · CNCapital Medical University · CNHuazhong University of Science and Technology · CNUnited States University · US

Funding

Hubei Science and Technology Support Program projects 2014BKB064
6 · The paper itself

Abstract

The present study aimed to detect selenium (Se) levels in the blood of Enshi Prefecture residents in China and investigate the relationship between blood Se levels and glucose or lipid metabolism disorder. A cross-sectional study was conducted, and 1876 subjects were selected through cluster random sampling from Enshi Prefecture using a questionnaire survey, physical examinations, and biochemical blood tests. The mean blood Se level in the overall population was 0.128 ± 0.178 μg/mL. Se exhibits a "U"-shaped curve on the serum fasting plasma glucose (FPG) of the total samples, that is, when the blood Se is more than 0.131 μg/mL or less than 0.062 μg/mL, the FPG increases significantly. A significant negative correlation was demonstrated between the FPG levels of the 4-17-year-old age group and different blood Se levels (P < 0.001). No significant correlation was demonstrated between the serum triglyceride (TG) and blood Se levels. However, a positive correlation was demonstrated between blood Se and serum total cholesterol (TC) levels and the incidence of high cholesterol in the total population (P < 0.001). The odds ratio and related 95% confidence interval for the incidence of high cholesterol between the highest (≥ 0.133 μg/mL) and lowest blood Se (< 0.064 μg/mL) levels was 2.64 and 1.48-4.79, respectively. The results of this study are very important for the safety scope and risk-benefit assessment of Se in the human; however, further investigation with a larger sample size is required.

Indexed as

SeleniumAdolescentBlood GlucoseChildChild, PreschoolChinaCross-Sectional StudiesFastingGlycolipidsHumansBlood GlucoseGlycolipidsSeleniumFasting plasma glucose (FPG)Glycolipid metabolismSelenium (Se)Total cholesterol (TC)Triglyceride (TG)

Identifiers

PMID33025519
OpenAlexW3092461981

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.