Evidence map›Paper›PMID 33025477›Full record

SynthesisJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2022

Diagnostic performance of prone-only myocardial perfusion imaging versus coronary angiography in the detection of coronary artery disease: A systematic review and meta-analysis.

Seyed Ali Mirshahvalad, Mohammadreza Chavoshi, Sepideh Hekmat

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Diagnostic performance of [European journal of nuclear medicine and molecular imaging · 2022
    Pooled it
  2. Significant myocardial perfusion defect during stress visible in prone but not in supine imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  3. Article
  4. Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2022: single photon emission computed tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Review
  5. Prone-only SPECT myocardial perfusion imaging: An alternative standard in clinical practice?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  6. Review
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Seyed Ali MirshahvaladResearch Center for Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-2271-9764
Mohammadreza ChavoshiDepartment of Radiology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0001-6598-7190
Sepideh HekmatDepartment of Nuclear Medicine, School of Medicine, Hasheminejad Hospital, Iran University of Medical Sciences, Vallinejad Alley, Valiasr Street, Tehran, Iran. sepidhekmat@hotmail.com.ORCID 0000-0002-0644-9349

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designAlthough prone position is considered as a complementary protocol in myocardial perfusion imaging (MPI), there is no consensus on its capability to find coronary artery disease (CAD), independently. The primary aim of this review was to report pooled sensitivity and specificity for prone position MPI in detection of CAD. In addition, the results were compared to the supine position's performance.

methodsElectronic bibliographic databases, The Cochrane Library, Web of Science (Science and Social Science Citation Index), Scopus, PubMed, and EMBASE until the end of June 2020 were searched. Studies were included based on the inclusion criteria of (1) evaluated the prone position MPI, (2) defined CAD with coronary angiography (CAG), using the threshold of ≥ 50% stenosis, (3) Adequate data were provided to extract the diagnostic performance. QUADAS-2 tool was utilized to assess the quality of included studies. Pooled sensitivity and specificity were calculated for prone and supine positions, separately. The hierarchical summary ROC curves were also drawn.

resultsTen individual studies with the data of the 1490 patients for the prone position and 1138 patients for the supine position were included. Pooled sensitivity and specificity for the prone position were 83% and 79%, respectively. These results were calculated for the supine position as the sensitivity of 86% and specificity of 67%. The pooled sensitivity and specificity of the prone position in detecting the right coronary artery territory defects were 70% and 84%, in turn.

conclusionIn the suspicion for the CAD, prone position with comparable sensitivity and higher specificity can be an acceptable alternative to the supine position as the standard method. Also, in the cases of possible defects in the RCA territory, prone position showed to be a superior standard.

Indexed as

Coronary Artery DiseaseMyocardial Perfusion ImagingCoronary AngiographyHumansSensitivity and SpecificityTomography, Emission-Computed, Single-Photoncoronary angiographyMeta-analysis. Coronary artery diseaseMyocardial perfusion imagingPooled sensitivityPooled specificityProne-only imagingprone positionsupine positionTc-99m

Identifiers

PMID33025477

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.