Evidence map›Paper›PMID 33025348›Full record

ArticleJournal of neurovirology2020

Status of humoral and cellular immune markers in human T-cell lymphotropic virus type 1 (HTLV-1) asymptomatic carriers in northeastern Iran, Mashhad.

Mohammad Reza Hedayati-Moghaddam, Farzad Mollahosseini, Mohammad Javad Namazi, Arman Mosavat, Seyed Abdolrahim Rezaee, Maryam Mahdifar, Hamid Reza Bidkhori, Narges Valizadeh, Houshang Rafatpanah

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neurovirology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mohammad Reza Hedayati-MoghaddamBlood Borne Infections Research Center, Academic Center for Education, Culture and Research (ACECR), Razavi Khorasan, Mashhad, Iran.ORCID 0000-0001-9133-5006
Farzad MollahosseiniIranian Blood Transfusion Organization, High Institute for Research and Education in Transfusion Medicine and Razavi Khorasan Blood Transfusion Center, Mashhad, Iran.
Mohammad Javad NamaziDepartment of Microbiology, Immunology and Parasitology, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.ORCID 0000-0001-5680-3919
Arman MosavatBlood Borne Infections Research Center, Academic Center for Education, Culture and Research (ACECR), Razavi Khorasan, Mashhad, Iran.ORCID 0000-0002-8408-4664
Seyed Abdolrahim RezaeeImmunology Research Center, Inflammation and Inflammatory Diseases Division, Faculty of Medicine, Mashhad University of Medical Sciences, Azadi-Square, Medical Campus, Mashhad, 9177948564, Iran.ORCID 0000-0001-6814-5992
Maryam MahdifarImmunology Research Center, Inflammation and Inflammatory Diseases Division, Faculty of Medicine, Mashhad University of Medical Sciences, Azadi-Square, Medical Campus, Mashhad, 9177948564, Iran.
Hamid Reza BidkhoriBlood Borne Infections Research Center, Academic Center for Education, Culture and Research (ACECR), Razavi Khorasan, Mashhad, Iran.ORCID 0000-0002-0204-0351
Narges ValizadehImmunology Research Center, Inflammation and Inflammatory Diseases Division, Faculty of Medicine, Mashhad University of Medical Sciences, Azadi-Square, Medical Campus, Mashhad, 9177948564, Iran.ORCID 0000-0003-4254-7314
Houshang RafatpanahImmunology Research Center, Inflammation and Inflammatory Diseases Division, Faculty of Medicine, Mashhad University of Medical Sciences, Azadi-Square, Medical Campus, Mashhad, 9177948564, Iran. RafatpanahH@mums.ac.ir.ORCID 0000-0002-1061-5864
Mashhad University of Medical Sciences · IRAcademic Center for Education, Culture and Research · IRHigh Institute for Education and Research in Transfusion Medicine · IRSabzevar University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is estimated that about 10-20 million peoples are infected with human T-cell leukemia virus type 1 (HTLV-1) around the world and suffered from HTLV-related diseases. The present study was aimed to evaluate the cellular immunity, T-cell activation, humoral immunity, and inflammatory response hallmarks which affect HTLV-1-associated disease progression. A total of 78 participants were included in the study, comprising 39 HTLV-1 asymptomatic careers (ACs) and 39 healthy controls. The HTLV-proviral load (PVL) was determined via real-time PCR technique, and anti-HTLV antibody, sIL2R, sCD30, Neoptrin, hs-CRP, IgE, anti-VCA, anti-EBNA, and anti-EA were assessed by ELISA method. Mean PVL in ACs was 352.7 ± 418.7 copies/10

Indexed as

Immunity, CellularImmunity, InnateAdultAntibodies, ViralAsymptomatic DiseasesCase-Control StudiesCD4-Positive T-LymphocytesC-Reactive ProteinFemaleHTLV-I InfectionsHumansHuman T-lymphotropic virus 1Immunoglobulin EInterleukin-2 Receptor alpha SubunitIranKi-1 AntigenAntibodies, ViralC-Reactive ProteinIL2RA protein, humanImmunoglobulin EInterleukin-2 Receptor alpha SubunitKi-1 AntigenNeopterinHTLV-1 asymptomatic careers (ACs)Human T-cell lymphotropic virus type 1 (HTLV-1)Immune markersNortheastern IranReal-time PCR (qRT-PCR)

Identifiers

PMID33025348
OpenAlexW3092557122

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.