Evidence map›Paper›PMID 33025277›Full record

ArticleMikrochimica acta2020

Surface plasmon resonance biosensor using hydrogel-AuNP supramolecular spheres for determination of prostate cancer-derived exosomes.

Wenqin Chen, Jia Li, Xiaotong Wei, Yunpeng Fan, Husun Qian, Siqiao Li, Yu Xiang, Shijia Ding

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 79 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Extracellular Vesicle Preparation and Analysis: A State-of-the-Art Review.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Current applications of nanomaterials in urinary system tumors.Frontiers in bioengineering and biotechnology · 2023
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Wenqin ChenKey Laboratory of Clinical Laboratory Diagnostics (Ministry of Education), College of Laboratory Medicine, Chongqing Medical University, Chongqing, 400016, China.
Jia LiKey Laboratory of Clinical Laboratory Diagnostics (Ministry of Education), College of Laboratory Medicine, Chongqing Medical University, Chongqing, 400016, China.
Xiaotong WeiKey Laboratory of Clinical Laboratory Diagnostics (Ministry of Education), College of Laboratory Medicine, Chongqing Medical University, Chongqing, 400016, China.
Yunpeng FanKey Laboratory of Clinical Laboratory Diagnostics (Ministry of Education), College of Laboratory Medicine, Chongqing Medical University, Chongqing, 400016, China.
Husun QianKey Laboratory of Clinical Laboratory Diagnostics (Ministry of Education), College of Laboratory Medicine, Chongqing Medical University, Chongqing, 400016, China.
Siqiao LiChongqing Engineering Research Center for Criminal Investigation Technology, Chongqing Medical University, Chongqing, 400016, China.
Yu XiangThe Department of Clinical Laboratory, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 40016, China.
Shijia DingKey Laboratory of Clinical Laboratory Diagnostics (Ministry of Education), College of Laboratory Medicine, Chongqing Medical University, Chongqing, 400016, China. dingshijia@163.com.ORCID 0000-0002-9183-1656
Chongqing Medical University · CNMinistry of Education · THThe Affiliated Yongchuan Hospital of Chongqing Medical University · CN

Funding

National Natural Science Foundation of China (CN) (81873980, 81873972)the Chongqing Medical University Graduate Talent Training Program (BJRC201908)the National Science and Technology Major Project of the Ministry of Science and Technology of China (2018ZX10732202)
6 · The paper itself

Abstract

Based on the hydrogel-AuNP supramolecular sphere (H-Au), a label-free and real-time surface plasmon resonance imaging biosensor has been developed for highly sensitive and specific determination of prostate cancer cell-derived exosomes. After integrating the signal amplification effect of the mass cumulative hydrogel and the LSPR effect of AuNPs with high specific aptamer, the SPRi biosensor for exosome detection exhibited a wide linear range from 1.00 × 10

Indexed as

Antigens, SurfaceAptamers, NucleotideBiosensing TechniquesCell Line, TumorDNAExosomesGlutamate Carboxypeptidase IIGoldHumansHydrogelsLimit of DetectionMaleMetal NanoparticlesProstatic NeoplasmsSurface Plasmon ResonanceAntigens, SurfaceAptamers, NucleotideDNAFOLH1 protein, humanGlutamate Carboxypeptidase IIGoldHydrogelsExosomesHydrogel-gold nanoparticles (hydrogel-AuNPs)Prostate-specific antigen (PSA)Surface plasmon resonance imaging (SPRi)Tumor diagnosis

Identifiers

PMID33025277
OpenAlexW3091808802

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.