Evidence map›Paper›PMID 33025211›Full record

ArticleMikrochimica acta2020

Platinum nanoflowers with peroxidase-like property in a dual immunoassay for dehydroepiandrosterone.

Huiyi Yang, Qiyi He, Yingshan Chen, Ding Shen, Huanxin Xiao, Sergei A Eremin, Xiping Cui, Suqing Zhao

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Biomedical Applications of Nanozymes: An Enzymology Perspective.Angewandte Chemie (International ed. in English) · 2025
    Review
  3. Article
  4. Review
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Huiyi YangDepartment of Pharmaceutical Engineering, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, People's Republic of China.
Qiyi HeDepartment of Pharmaceutical Engineering, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, People's Republic of China.
Yingshan ChenDepartment of Pharmaceutical Engineering, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, People's Republic of China.
Ding ShenDepartment of Pharmaceutical Engineering, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, People's Republic of China.
Huanxin XiaoDepartment of Pharmaceutical Engineering, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, People's Republic of China.
Sergei A EreminFaculty of Chemistry, M. V. Lomonosov Moscow State University, 119991, Moscow, Russia.
Xiping CuiDepartment of Pharmaceutical Engineering, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, People's Republic of China. cuixiping1989@163.com.
Suqing ZhaoDepartment of Pharmaceutical Engineering, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, People's Republic of China. sqzhao@gdut.edu.cn.ORCID 0000-0002-8458-671X

Funding

Guangdong Science and Technology Foundation 2017A050501034Guangzhou Science and Technology Foundation 2016201604030025Ministry of Education and Science of the Russian Federation 14.604.21.0198
6 · The paper itself

Abstract

Platinum nanoflowers (PtNFs) were utilized in a competitive enzyme-linked immunosorbent assay (ELISA) and in a lateral flow immunoassay (LFIA) for superior peroxidase-like activity and intense brown color, respectively. PtNFs were linked to the polyclonal antibody (pAb) to form the pAb-PtNFs probes for the dual immunoassay. Based on optimized pAb-PtNF probes, both enzyme-linked immunosorbent assay (PtNFs-ELISA) and lateral flow immunoassay (PtNFs-LFIA) perform very well. The absorbance at 450 nm decreases linearly in the DHEA concentration range 2.1 to 118.1 ng mL

Indexed as

Antibodies, ImmobilizedBenzidinesCatalysisChromogenic CompoundsColorimetryDehydroepiandrosteroneEnzyme-Linked Immunosorbent AssayHumansHydrogen PeroxideLimit of DetectionMetal NanoparticlesOxidation-ReductionPlatinum3,3',5,5'-tetramethylbenzidineAntibodies, ImmobilizedBenzidinesChromogenic CompoundsDehydroepiandrosteroneHydrogen PeroxidePlatinumDehydroepiandrosterone (DHEA)ELISAImmunoassaysLFIAPlatinum nanoflowers (PtNFs)Polyclonal antibody

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.