ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2021
Radiographic cervical spine degenerative findings: a study on a large population from age 18 to 97 years.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Comparison of skip-level ACDF vs. contiguous ACDF in the treatment of skip-level cervical degenerative disease: a systematic review and meta-analysis.Frontiers in surgery · 2026Pooled it
- Quantitative assessment of bone mineral density in cervical spine surgery: Diagnostic accuracy of C2 and C3 Hounsfield units versus cervical vertebral bone quality scores.North American Spine Society journal · 2026Article
- Predictors of surgical site infection after anterior cervical discectomy and fusion in a national administrative database.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Single-level cervical disc arthroplasty is associated with higher early subsequent surgery rates and similar adjacent segment disease rates compared with anterior cervical discectomy and fusion.Journal of spine surgery (Hong Kong) · 2026Article
- Article
- Spinal cord reserve is associated with multi-dimensional clinical resilience in multiple sclerosis.Journal of neurology · 2026Article
- Pain catastrophizing and postoperative satisfaction in cervical disc herniation: a 6-month prospective cohort study.BMC musculoskeletal disorders · 2026Article
- Intervertebral disc degeneration.Nature reviews. Disease primers · 2026Review
- Cervical Spine Degeneration in Rugby Players: Position-Specific Differences in Radiographic and Clinical Outcomes Among 64 Brazilian Athletes.Journal of functional morphology and kinesiology · 2026Article
- Assessing cervical intervertebral disc height on MRI and X-ray versus CT; a single center retrospective cohort study.Brain & spine · 2026Article
- Identification of immune-mediated aging genes associated with cervical spondylosis through single-cell eQTL Mendelian randomization.Frontiers in immunology · 2026Article
- Multisensory Integration for Identifying the Milling States in Robot-Assisted Cervical Laminectomy.Orthopaedic surgery · 2025Article
- Effectiveness of various anterior noncontiguous cervical spine surgeries for treatment of noncontiguous cervical degenerative disk disease: a network meta-analysis.Asian spine journal · 2025Article
- Intervertebral disc degeneration, age, and sex affect the range of motion of the cervical spine.Scientific reports · 2025Article
- Computed Tomography Prevalence of Cervicothoracic Endplate Junction Alterations in Dogs.Animals : an open access journal from MDPI · 2025Article
- Current and future advances in practice: cervical spondylosis and mechanical neck pain.Rheumatology advances in practice · 2025Review
- Biomechanical Evaluation of Cervical Interbody Fusion Cages for Anterior Cervical Discectomy and Fusion With Variations in Morphology: A Finite Element Analysis.Biomedical engineering and computational biology · 2025Article
- The footprint mismatch of cervical disc arthroplasty comes from degenerative factor besides ethnic factor.Scientific reports · 2024Article
- Restoration of Range of Motion in the Cervical Spine through Single-Segment Artificial Disc Replacement Using the BagueraJournal of clinical medicine · 2024Article
- Impact of neck posture and insulating stick use on neck disability in Korean line workers: a cross-sectional study.Annals of occupational and environmental medicine · 2024Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aims of this study were (1) to determine the prevalence of radiographic cervical disc degeneration in a large population of patients aged from 18 to 97 years; (2) to investigate individually the prevalence and distribution of height loss, osteophyte formation, endplate sclerosis and spondylolisthesis; and (3) to describe the patterns of cervical disc degeneration.
methodsA retrospective study was performed. Standard lateral cervical spine radiographs in standing, neutral position of 1581 consecutive patients (723 males, 858 females) with an average age of 41.2 ± 18.2 years were evaluated. Cervical disc degeneration was graded from C2/C3 to C6/C7 based on a validated quantitative grading system. The prevalence and distribution of radiographic findings were evaluated and associations with age were investigated.
results53.9% of individuals had radiographic disc degeneration and the most affected level was C5/C6. The presence and severity of disc degeneration were found to be significantly associated with age both in male and female subjects. The most frequent and severe occurrences of height loss, osteophyte formation, and endplate sclerosis were at C5/C6, whereas spondylolisthesis was most observed at C4/C5. Age was significantly correlated with radiographic degenerative findings. Contiguous levels degeneration pattern was more likely found than skipped level degeneration. The number of degenerated levels was also associated with age.
conclusionsThe presence and severity of radiographic disc degeneration increased with aging in the cervical spine. Older age was associated with greater number of degenerated disc levels. Furthermore, the correlations between age and the degree of degenerative findings were stronger at C5/C6 and C6/C7 than at other cervical spinal levels.
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