Evidence map›Paper›PMID 33025134›Full record

ReviewDer Radiologe2020

[Proton therapy-a chance in the treatment of tumors of the head and neck and base of skull].

Beate Timmermann

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Radiologe, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Beate TimmermannKlinik für Partikeltherapie, Westdeutsches Protonentherapiezentrum Essen, Universitätsklinikum Essen, Hufelandstr. 55, 45147, Essen, Deutschland. beate.timmermann@uk-essen.de.
Essen University Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRadiotherapy (RT) is an integral part of the treatment of many tumors located in the vicinity of sensitive organs and structures, including tumors of the head and neck and base of skull in particular. Due to the risk of side effects associated with RT, the use of highly conformal RT techniques is favored. For many indications, proton therapy (PT) is therefore already part of the modern treatment standard.

objectiveThis article presents an overview of current indications for PT with emphasis on tumors in the head and neck region and the base of skull. Furthermore, a summary and discussion of relevant results and current developments are included. MATERIALS AND

methodsThe work comprises an evaluation of relevant studies and an overview of current issues related to PT of tumors in the areas of the head, neck, and base of skull.

resultsOverall, the studies on PT show promising results. In addition to dosimetric studies, clinical studies also point to advantages of PT, especially with regard to the reduction of side effects. DISCUSSION: Currently, use of the model-based approach is being discussed. This is intended to identify those patients who benefit most from PT based on the normal tissue complication probability (NTCP). PT for re-RT is also discussed.

Indexed as

Head and Neck NeoplasmsProton TherapySkull Base NeoplasmsHumansProbabilityRadiotherapy DosageSkull BaseCombined modality therapyNeoplasmsRadiotherapySarcomaTreatment outcome

Identifiers

PMID33025134
OpenAlexW3092408554

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.