ArticleJournal of Alzheimer's disease reports2020
Long-Term, All-Day Exposure to Circadian-Effective Light Improves Sleep, Mood, and Behavior in Persons with Dementia.
Article in Journal of Alzheimer's disease reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 53 citations in OpenAlex.
- Biodynamic lighting versus bright light effects on rest-activity rhythm and night-time sleep in nursing homes residents with dementia.BMC geriatrics · 2026Trial
- Effects of light therapy on sleep and circadian rhythm in older type 2 diabetics living in long-term care facilities: a randomized controlled trial.Frontiers in endocrinology · 2024Trial
- Enhancing a Behavioral Intervention Using Rest-Activity Rhythm Monitoring via a Consumer Wearable in Older Dementia Caregivers and People With Dementia: Feasibility and Acceptability Study.JMIR formative research · 2026Article
- Neuropsychiatric Symptoms in Primary Progressive Aphasia: Phenomenology, Circuits, and Clinical Management.Current neurology and neuroscience reports · 2026Review
- Home-Based Tailored Light Therapy for Sleep, Mood, and Cognitive Outcomes in Mild Cognitive Impairment: A Randomized Trial.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026Article
- Light Exposure as a Modifiable Determinant of Mental Health.Current psychiatry reports · 2026Review
- Outdoor light at night and neuropsychiatric symptoms in dementia.GeroScience · 2026Article
- Developing a structured framework to explore the experiences of people with dementia and their caregivers regarding non-pharmacological sleep interventions.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Circadian Rhythms in Aging and Age-Related Neurogenerative Disease.Current sleep medicine reports · 2025Article
- Using Wearable Sensors to Measure and Predict Personal Circadian Lighting Exposure in Nursing Home Residents: Model Development and Validation.JMIR aging · 2025Article
- More Than Rapid Eye Movement Sleep Behavior Disorder: Sleep Differences in Parkinson's Disease LRRK2 and GBA Genotypes.Journal of sleep medicine · 2025Article
- Effectiveness of Nature-Based Interventions in Reducing Agitation Among Older Adults with Dementia: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2025Review
- Wearables in Chronomedicine and Interpretation of Circadian Health.Diagnostics (Basel, Switzerland) · 2025Review
- Tailored light intervention for sleep and cognition in World Trade Center (WTC) cohort.Archives of environmental & occupational health · 2025Article
- Sleep Across the Lifespan: A Neurobehavioral Perspective.Current sleep medicine reports · 2025Review
- Evaluating the Impact of a Daylight-Simulating Luminaire on Mood, Agitation, Rest-Activity Patterns, and Social Well-Being Parameters in a Care Home for People With Dementia: Cohort Study.JMIR mHealth and uHealth · 2024Article
- Investigating the effects of indoor lighting on measures of brain health in older adults: protocol for a cross-over randomized controlled trial.BMC geriatrics · 2024Article
- Examining the Relationships Between Indoor Environmental Quality Parameters Pertaining to Light, Noise, Temperature, and Humidity and the Behavioral and Psychological Symptoms of People Living With Dementia: Scoping Review.Interactive journal of medical research · 2024Article
- Postoperative cognitive dysfunction: spotlight on light, circadian rhythms, and sleep.Frontiers in neuroscience · 2024Review
- Effect of Personalized Blue-Enriched White Light Intervention on Rest-Activity and Light Exposure Rhythms in Mild and Moderate Alzheimer's Disease.Psychiatry investigation · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPersons with Alzheimer's disease and related dementias (ADRD) frequently experience sleep-wake (circadian) cycle disturbances that lead them to remain awake at night, causing stress and fatigue for families and caregivers. Light therapy shows promise as a nonpharmacological treatment for regulating sleep in this population.
objectiveWe investigated the long-term impact of a circadian-effective lighting intervention on sleep, mood, and behavior problems in persons with ADRD.
methodsThis 25-week clinical trial administered an all-day lighting intervention to 47 patients with ADRD in 9 senior-care facilities, employing wrist-worn actigraphy measures and standardized measures of sleep quality, mood, and behavior.
resultsThe intervention significantly improved Pittsburgh Sleep Quality Index scores, from an estimated mean±SEM of 11.89±0.53 at baseline to 5.36±0.63 at the end of the intervention. Additional improvements were noted for sleep efficiency data from actigraph measurements. The intervention significantly reduced Cornell Scale for Depression in Dementia scores (mean±SEM of 11.36±0.74 at baseline and 4.18±0.88 at the end of the intervention) and Cohen-Mansfield Agitation Inventory scores (mean±SEM of 47.10±1.98 at baseline and 35.33±2.23 at the end of the intervention).
conclusionA regular circadian-effective daytime lighting intervention can improve sleep at night and reduce depression and agitation in patients with dementia living in controlled environments. More importantly, the positive effects of the tailored lighting intervention on these outcomes appear to be cumulative over time.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.