Evidence map›Paper›PMID 33024918›Full record

ArticleHepatology communications2020

Deficiency of miR-208a Exacerbates CCl

Shashi Bala, Charles D Calenda, Donna Catalano, Mrigya Babuta, Karen Kodys, Imad A Nasser, Barbara Vidal, Gyongyi Szabo

Open access · goldAbstract read
In one paragraph

Article in Hepatology communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. miRNAs in HCC, pathogenesis, and targets.Hepatology (Baltimore, Md.) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Shashi BalaDepartment of Medicine Beth Israel Deaconess Medical Center Harvard Medical School Boston MA.
Charles D CalendaDepartment of Medicine Beth Israel Deaconess Medical Center Harvard Medical School Boston MA.
Donna CatalanoDepartment of Medicine University of Massachusetts Medical School Worcester MA.
Mrigya BabutaDepartment of Medicine Beth Israel Deaconess Medical Center Harvard Medical School Boston MA.ORCID https://orcid.org/0000-0001-8420-4796
Karen KodysDepartment of Medicine University of Massachusetts Medical School Worcester MA.
Imad A NasserDepartment of Medicine Beth Israel Deaconess Medical Center Harvard Medical School Boston MA.
Barbara VidalDepartment of Medicine Beth Israel Deaconess Medical Center Harvard Medical School Boston MA.
Gyongyi SzaboDepartment of Medicine Beth Israel Deaconess Medical Center Harvard Medical School Boston MA.
Beth Israel Deaconess Medical Center · USUniversity of Massachusetts Chan Medical School · US

Funding

STRUCTURE-FUNCTION RELATIONSHIPS IN THE ALIMENTARY TRACTP30DK034854 · NIDDK · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI JONATHAN C KAGAN · 1986 to 2026
$32.4M
MicroRNAs in Alcoholic Liver Disease Administrative SupplementR01AA020744 · NIAAA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SZABO, GYONGYI · 2011 to 2023
$5.3M
Biomarkers of Disease in Alcoholic Hepatitis Administrative SupplementU01AA026933 · NIAAA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SZABO, GYONGYI · 2018 to 2023
$1.4M
Extracellular Vesicles in Alcoholic Liver Disease: Basic and Pre-Clinical DiscoveryUH2AA026970 · NIAAA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SZABO, GYONGYI · 2018 to 2019
$461k
NIAAA NIH HHS R01 AA020744NIAAA NIH HHS U01 AA026933NIAAA NIH HHS UH2 AA026970NIDDK NIH HHS P30 DK034854
6 · The paper itself

Abstract

Acute liver injury (ALI) is associated with multiple cellular events such as necrosis, apoptosis, oxidative stress and inflammation, which can lead to liver failure. In this study, we demonstrate a new role of microRNA (miR)-208a in ALI. ALI was induced in wild-type (WT) and miR-208a knockout (KO) mice by CCl

Identifiers

PMID33024918
PMCPMC7527689
OpenAlexW3059794013

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.