Evidence map›Paper›PMID 33024774›Full record

ArticleWorld journal of clinical cases2020

Nonasthmatic eosinophilic bronchitis in an ulcerative colitis patient - a putative adverse reaction to mesalazine: A case report and review of literature.

Andrei Tudor Cernomaz, Gabriela Bordeianu, Cristina Terinte, Cristina Maria Gavrilescu

Open access · diamondAbstract readCase Reports
In one paragraph

Article in World journal of clinical cases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Andrei Tudor CernomazDepartment of Internal Medicine, Grigore T. Popa University of Medicine and Pharmacy, Iasi 700115, Romania. tudor.cernomaz@umfiasi.ro.
Gabriela BordeianuDepartment of Biochemistry, Grigore T. Popa University of Medicine and Pharmacy, Iasi 700115, Romania.
Cristina TerinteDepartment of Pathology, Regional Oncology Institute, Iasi 700483, Romania.
Cristina Maria GavrilescuDepartment of Internal Medicine, Grigore T. Popa University of Medicine and Pharmacy, Iasi 700115, Romania.
Grigore T. Popa University of Medicine and Pharmacy · ROInstitutul Regional de Oncologie · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLung and airway involvement in inflammatory bowel disease are increasingly frequently reported either as an extraintestinal manifestation or as an adverse effect of therapy. CASE SUMMARY: We report a case of a patient with ulcerative colitis controlled under mesalazine treatment who presented with chronic cough and hemoptysis. Chest computed tomography and bronchoscopy findings supported tracheal involvement in ulcerative colitis; pathology examination demonstrated an unusual eosinophil-rich inflammatory pattern, and together with clinical data, a nonasthmatic eosinophilic bronchitis diagnosis was formulated. Full recovery was observed within days of mesalazine discontinuation.

conclusionMesalazine-induced eosinophilic respiratory disorders have been previously reported, generally involving the lung parenchyma. To the best of our knowledge, this is the first report of mesalamine-induced eosinophilic involvement in the upper airway.

Indexed as

BronchitisCase reportDrug-related side effectsHemoptysisMesalamineUlcerative colitis

Identifiers

PMID33024774
PMCPMC7520771
OpenAlexW3088833197

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.