Evidence map›Paper›PMID 33024760›Full record

ArticleWorld journal of clinical cases2020

Pre- and intraoperative predictors of acute kidney injury after liver transplantation.

Anna Mrzljak, Lucija Franusic, Jadranka Pavicic-Saric, Tomislav Kelava, Zeljka Jurekovic, Branislav Kocman, Danko Mikulic, Ivan Budimir-Bekan, Mladen Knotek

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Article in World journal of clinical cases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Anna MrzljakDepartment of Medicine, Merkur University Hospital, School of Medicine, University of Zagreb, Zagreb 10000, Croatia. anna.mrzljak@mef.hr.
Lucija FranusicGeneral Hospital Dubrovnik, Dubrovnik 20000, Croatia.
Jadranka Pavicic-SaricDepartment of Anesthesiology and Intensive Medicine, Merkur University Hospital, School of Medicine, University of Zagreb, Zagreb 10000, Croatia.
Tomislav KelavaLaboratory for Molecular Immunology, Croatian Institute for Brain Research, University of Zagreb, School of Medicine, Zagreb 10000, Croatia.
Zeljka JurekovicDepartment of Medicine, Merkur University Hospital, Zagreb 10000, Croatia.
Branislav KocmanDepartment of Surgery, Merkur University Hospital, Zagreb 10000, Croatia.
Danko MikulicDepartment of Surgery, Merkur University Hospital, Zagreb 10000, Croatia.
Ivan Budimir-BekanDepartment of Surgery, Merkur University Hospital, Zagreb 10000, Croatia.
Mladen KnotekDepartment of Medicine, Merkur University Hospital, School of Medicine, University of Zagreb, Zagreb 10000, Croatia.
Klinička bolnica Merkur · HRUniversity of Zagreb · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) after liver transplantation (LT) is a frequent and multifactorial event related to increased morbidity and mortality. Risk factors for AKI after LT still need to be clarified.

aimTo identify the predictors of acute kidney injury after liver transplantation.

methodsThe frequency and pre- and intraoperative predictors of AKI within the first 7 d after LT were evaluated in adult liver transplant candidates in a single LT center in Croatia. AKI was defined according to the Kidney Disease: Improving Global Outcomes criteria.

resultsOut of 205 patients (mean age 57 ± 10 years; 73.7% males, 52.7% with alcohol-related liver disease) 93 (45.36%) developed AKI, and the majority of them (58.06%) had stage 1. Only 5.38% of patients required renal replacement therapy after LT. The majority of patients (82.8%) developed AKI within the first two days after the procedure. Multivariate logistic regression identified pre-LT body mass index (OR = 1.1, 95%CI: 1.05-1.24) and red blood cell transfusion (OR = 1.66, 95%CI: 1.09-2.53) as independent predictors of early post-LT AKI occurrence. 30-d survival after LT was significantly better for patients without AKI (

conclusionEarly AKI after LT is a frequent event that negatively impacts short-term survival. The pathogenesis of AKI is multifactorial, but pre-LT BMI and intraoperative volume shifts are major contributors.

Indexed as

Acute kidney injuryBody mass indexLiver transplantRed blood cellSurvival

Identifiers

PMID33024760
PMCPMC7520778
OpenAlexW3089194351

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.