Evidence map›Paper›PMID 33024691›Full record

ArticleRespiratory medicine case reports2020

Levetiracetam-induced interstitial lung disease in a patient with advanced lung cancer.

Shintaro Sato, Tomohiro Oba, Hiroki Ohta, Yuta Tsukahara, Gen Kida, Emiri Tsumiyama, Kenji Kusano, Tomotaka Nishizawa, Rie Kawabe, Hideaki Yamakawa and 3 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory medicine case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Recipient Comorbidities for Prediction of Primary Graft Dysfunction, Chronic Allograft Dysfunction and Survival After Lung Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Shintaro SatoDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan.
Tomohiro ObaDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan.
Hiroki OhtaDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan.
Yuta TsukaharaDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan.
Gen KidaDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan.
Emiri TsumiyamaDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan.
Kenji KusanoDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan.
Tomotaka NishizawaDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan.
Rie KawabeDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan.
Hideaki YamakawaDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan.
Keiichi AkasakaDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan.
Masako AmanoDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan.
Hidekazu MatsushimaDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan.
Saitama Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An 85-year-old woman with antibiotics-resistant pneumonia after surgery for metastatic brain tumor from lung cancer was consulted to our department. Chest CT showed diffuse GGO bilaterally. BALF showed elevated ratios of lymphocytes and CD4/CD8. Tests for bacteria, mycobacteria, and fungi were negative. She improved following levetiracetam discontinuance and systemic corticosteroid administration, and we diagnosed levetiracetam-induced lung injury. Although levetiracetam is widely used, few reports of levetiracetam-induced pneumonia exist. Changes in chest images may occur after levetiracetam administration if patients have multiple risk factors for development of drug-induced interstitial lung disease. Bronchoscopy is useful for differential diagnosis if new lung lesions appear after starting levetiracetam.

Indexed as

AED, antiepileptic drugBALF, bronchoalveolar lavage fluidDrug-induced interstitial lung diseaseEGFR, epidermal growth factor receptorGGO, ground-glass opacityILD, interstitial lung diseaseLevetiracetamLEV, levetiracetamLung cancer

Identifiers

PMID33024691
PMCPMC7528199
OpenAlexW3089701143

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.