Evidence map›Paper›PMID 33024690›Full record

ArticleRespiratory medicine case reports2020

Successful treatment for a patient with chronic thromboembolic pulmonary hypertension comorbid with essential thrombocythemia with the JAK2 V617F mutation by balloon pulmonary angioplasty.

Tomohiro Yamaguchi, Yasuhiro Izumiya, Hiroya Hayashi, Yoshitaka Ichikawa, Hirotoshi Ishikawa, Atsushi Shibata, Takanori Yamazaki, Minoru Yoshiyama

Open access · goldAbstract readCase Reports
In one paragraph

Article in Respiratory medicine case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tomohiro YamaguchiDepartment of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
Yasuhiro IzumiyaDepartment of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
Hiroya HayashiDepartment of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
Yoshitaka IchikawaDepartment of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
Hirotoshi IshikawaDepartment of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
Atsushi ShibataDepartment of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
Takanori YamazakiDepartment of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
Minoru YoshiyamaDepartment of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
Osaka City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A-71-year-old woman was diagnosed as chronic thromboembolic pulmonary hypertension (CTEPH) accompanied by essential thrombocythemia (ET) with JAK2 V617F mutation. Blood test showed remarkable increase of platelet counts (132.9 × 10^4/μL) and elevated plasma BNP level (125.1pg/mL). Right heart catheterization (RHC) revealed remarkably high mean pulmonary arterial pressure (mPAP) of 43 mmHg. We gave her riociguat of 7.5mg, oral anticoagulants, oxygen inhalation for CTEPH, and anagrelide for ET. We performed 4 sessions of balloon pulmonary angioplasty (BPA) in 9 months RHC revealed successful hemodynamic improvement (mPAP = 21 mmHg) after final BPA procedure without riociguat. At six month later after final BPA procedure, RHC showed steadily improvement of mPAP (21 mmHg) without riociguat and oxygen inhalation. She lives well without oxygen inhalation and PH targeted therapy. This is the first report of successful treatment for a patient with CTEPH comorbid with ET with JAK2 V617F mutation by BPA.

Indexed as

6MWT, 6-min walking testBalloon pulmonary angioplastyBNP, Brain natriuretic peptideBPA, balloon pulmonary angioplastyChronic thromboembolic pulmonary hypertensionCTEPH, chronic thromboembolic pulmonary hypertensionEssential thrombocythemiaET, essential thrombocythemiamPAP, mean pulmonary arterial pressurePEA, pulmonary endarterectomyPH, pulmonary hypertensionRHC, right heart catheterization

Identifiers

PMID33024690
PMCPMC7528185
OpenAlexW3090301626

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.