Evidence map›Paper›PMID 33024544›Full record

ArticleJournal of venom research2020

Snake C-type lectin-like proteins inhibit nicotinic acetylcholine receptors.

Elena V Kryukova, Catherine A Vulfius, Rustam H Ziganshin, Tatyana V Andreeva, Vladislav G Starkov, Victor I Tsetlin, Yuri N Utkin

Registry-linked trialAbstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of venom research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07727668 (Feasibility Study of Iberdomide), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07727668 early_phase1not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Feasibility Study of Iberdomide (CC-220) Priming to Improve T Cell Fitness Prior to Leukapheresis for Chimeric Antigen Receptor T Cell (CAR-T) Therapy for Relapsed/Refractory Multiple Myeloma (RRMM)

TypeinterventionalSponsorShambavi RichardRan2026 to 2031Enrolled22ConditionsMultiple Myeloma, Relapsed/Refractory Multiple MyelomaArmsIberdomide, CAR-T Leukapheresis, CAR-T Infusion
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. What Are the Neurotoxins in Hemotoxic Snake Venoms?International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elena V KryukovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow 117997, Russia.
Catherine A VulfiusInstitute of Cell Biophysics Russian Academy of Sciences, 3 Institutskaya Street, Pushchino Moscow region, 142290, Russia.
Rustam H ZiganshinShemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow 117997, Russia.
Tatyana V AndreevaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow 117997, Russia.
Vladislav G StarkovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow 117997, Russia.
Victor I TsetlinShemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow 117997, Russia.
Yuri N UtkinShemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow 117997, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Venoms of viperid snakes affect mostly hemostasis, while C-type lectin-like proteins (CTLPs), one of the main components of viperid venoms, act as anticoagulants, procoagulants, or agonists/antagonists of platelet activation. However, we have shown earlier that CTLPs from the saw-scaled viper

Indexed as

C-type lectin-like proteinnicotinic acetylcholine receptorsaw-scaled vipersnakevenomα-bungarotoxin

Identifiers

PMID33024544
PMCPMC7512478

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.