Evidence map›Paper›PMID 33024515›Full record

ReviewWorld journal of biological chemistry2020

Immunological aspects of COVID-19: What do we know?

Tsvetelina Veselinova Velikova, Stanislav Vasilev Kotsev, Daniel Stefanov Georgiev, Hristiana Momchilova Batselova

Open access · diamondAbstract readReview
In one paragraph

Review in World journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. COVID-19 related liver injuries in pregnancy.World journal of clinical cases · 2023
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Frontiers in immunology · 2022
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. [SARS-CoV-2 reinfection].Medicina intensiva
    Article
  20. SARS-CoV-2 reinfection.Medicina intensiva
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Tsvetelina Veselinova VelikovaDepartment of Clinical Immunology, University Hospital Lozenetz, Sofia 1407, Bulgaria. tsvelikova@medfac.mu-sofia.bg.
Stanislav Vasilev KotsevDepartment of Infectious Diseases, Pazardzhik Multiprofile Hospital for Active Treatment, Pazardzhik 4400, Bulgaria.
Daniel Stefanov GeorgievDental Faculty, Medical University of Plovdiv, Plovdiv 4002, Bulgaria.
Hristiana Momchilova BatselovaDepartment of Epidemiology and Disaster Medicine, Medical University, Plovdiv, University Hospital "St George", Plovdiv 4002, Bulgaria.
Medical University Plovdiv · BGLozenetz Hospital · BGNational Institute of Emergency Medicine "Pirogov" · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The newly emerged coronavirus (severe acute respiratory syndrome coronavirus 2 SARS-CoV-2) and the disease that it causes coronavirus disease 2019 (COVID-19) have changed the world we know. Yet, the origin and evolution of SARS-CoV-2 remain mostly vague. Many virulence factors and immune mechanisms contribute to the deteriorating effects on the organism during SARS-CoV-2 infection. Both humoral and cellular immune responses are involved in the pathophysiology of the disease, where the principal and effective immune response towards viral infection is the cell-mediated immunity. The clinical picture of COVID-19, which includes immune memory and reinfection, remains unclear and unpredictable. However, many hopes are put in developing an effective vaccine against the virus, and different therapeutic options have been implemented to find effective, even though not specific, treatment to the disease. We can assume that the interaction between the SARS-CoV-2 virus and the individual's immune system determines the onset and development of the disease significantly.

Indexed as

Anti-SARS-CoV-2 antibodiesCOVID-19COVID-19 treatmentImmune memoryPlasma therapySARS-CoV-2

Identifiers

PMID33024515
PMCPMC7520644
OpenAlexW3088145579

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.