Evidence map›Paper›PMID 33024505›Full record

ArticleJournal of atrial fibrillation

Role of Ganglionated Plexus Ablation in Atrial Fibrillation on the Basis of Supporting Evidence.

Carina Hardy, Esteban Rivarola, Mauricio Scanavacca

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Journal of atrial fibrillation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05572034 (Cardiac Autonomic Denervation for Cardio-inhibitory Syncope), which is not on this map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05572034 naunknown statusnot on this map

Cardiac Autonomic Denervation for Cardio-inhibitory Syncope

TypeinterventionalSponsorUniversity of Sao Paulo General HospitalRan2023 to 2024Enrolled45ConditionsBradycardia, Syncope, Syncope, VasovagalArmsElectrophysiological study, Electrophysiological study and Right side Ganglionated Plexi ablation, Electrophysiological study and bi-atrial Ganglionated Plexi ablation
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pulmonary vein isolation with adjunctive left atrial ganglionic plexus ablation for treatment of atrial fibrillation: a meta-analysis of randomized controlled trials.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Pooled it
  2. Pooled it
  3. Management of atrial fibrillation: two decades of progress - a scientific statement from the European Cardiac Arrhythmia Society.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2022
    Review
  4. Pulmonary vein isolation in a real-world population does not influence QTc interval.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Carina HardyHeart Institute- University of Sao Paulo Medical School, Brazil.
Esteban RivarolaHeart Institute- University of Sao Paulo Medical School, Brazil.
Mauricio ScanavaccaHeart Institute- University of Sao Paulo Medical School, Brazil.
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of the autonomic nervous system (ANS) in the onset and maintenance of atrial fibrillation (AF) may be related to autonomic imbalance. The ANS may cause specific cellular electrophysiological phenomena, such as, shortening of the atrial effective refractory periods (ERPs) and ectopy based on firing activity in pulmonary vein myocytes. High frequency stimulation of atrial ganglionated plexi (GPs) may cause an increase in ERP dispersion and induce AF. Autonomic modification strategies by targeting GPs with catheter ablation have emerged as new targets. Various strategies have been used to detect location of GPs.However, it is still not clear which is the best method to localize GPs, how many GPs should be targeted, and what are the long-term consequences of these therapies. In this review, we discuss available evidence on the clinical impact of GP ablation to treat AF.

Indexed as

Atrial fibrillationAutonomic nervous systemCardiac denervation

Identifiers

PMID33024505
PMCPMC7533146
OpenAlexW3091846672

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.